SCHEMBL3754154

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3751654	0.93	HIF1A (0.52)	HIF1ANPC1RAB9ANR4A2MEN1
	SCHEMBL3759610	0.92	HIF1A (0.51)	HIF1ANPC1RAB9ANR4A2MEN1
	SCHEMBL3759713	0.90	HIF1A (0.49)	HIF1ANPC1RAB9ANR4A2MEN1
	SCHEMBL3751696	0.89	NR1H4 (0.43)	HIF1ANR4A2MEN1KMT2AKDM4E
	SCHEMBL3755609	0.83	NR1H4 (0.45)	HIF1ANR4A2MEN1KMT2AKDM4E
	SCHEMBL8618332	0.82	HIF1A (0.50)	HIF1ANR4A2KDM4ESMN1; SMN2
	SCHEMBL8618330	0.82	HIF1A (0.50)	HIF1ANR4A2KDM4ESMN1; SMN2
	SCHEMBL3754149	0.82	HIF1A (0.74)	HIF1ANPC1RAB9ASPHK2SPHK1
	SCHEMBL3752980	0.81	NR1H4 (0.45)	HIF1ANPC1RAB9ANR4A2MEN1
	SCHEMBL3689830	0.81	HIF1A (0.42)	HIF1ANPC1RAB9ANR4A2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.