Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.42 |
| ▸ | FDPS | P14324 | 3/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hexane SCHEMBL1145162 | 1.00 | TSHR (0.50) | TSHRTHRBLMNADNM1OPRM1 | |
| SCHEMBL26106 | 1.00 | — | — | |
| SCHEMBL7574727 | 1.00 | TSHR (0.50) | TSHRTHRBLMNADNM1OPRM1 | |
| Hexane SCHEMBL17747414 | 1.00 | TSHR (0.50) | TSHRTHRBLMNADNM1OPRM1 | |
| SCHEMBL16969849 | 1.00 | TSHR (0.50) | TSHRTHRBLMNADNM1OPRM1 | |
| SCHEMBL154425 | 1.00 | TSHR (0.50) | TSHRTHRBLMNADNM1OPRM1 | |
| SCHEMBL688498 | 1.00 | TSHR (0.50) | TSHRTHRBLMNADNM1OPRM1 | |
| Hexane SCHEMBL1525236 | 1.00 | TSHR (0.50) | TSHRTHRBLMNADNM1OPRM1 | |
| Heptane SCHEMBL15226631 | 1.00 | TSHR (0.50) | TSHRTHRBLMNADNM1OPRM1 | |
| SCHEMBL977939 | 1.00 | TSHR (0.50) | TSHRTHRBLMNADNM1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4223761-A1 | QUINAZOLINE COMPOUND AND APPLICATION THEREOF | Shanghai Pharmaceuticals Holding Co., Ltd. (CN) | 2023-08-09 | — | — | EP | claimed |
| CN-116323624-A | Quinazoline compound and application thereof | 上海医药集团股份有限公司 | 2023-06-23 | — | — | CN | claimed |
| WO-2024071415-A1 | COMPOUND, METAL COMPLEX, CATALYST COMPOSITION FOR OLEFIN POLYMERIZATION, CATALYST FOR OLEFIN POLYMERIZATION AND METHOD FOR PRODUCING OLEFIN POLYMER | 日本ポリケム株式会社 | 2024-04-04 | — | — | WO | disclosed |
| US-20230365563-A1 | QUINAZOLINE COMPOUND AND APPLICATION THEREOF | SHANGHAI PHARMACEUTICALS HOLDING CO., LTD. (CN) | 2023-11-16 | — | — | US | disclosed |
| EP-4223761-A1 | QUINAZOLINE COMPOUND AND APPLICATION THEREOF | Shanghai Pharmaceuticals Holding Co., Ltd. (CN) | 2023-08-09 | — | — | EP | disclosed |
| CN-116323624-A | Quinazoline compound and application thereof | 上海医药集团股份有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-115260158-A | Compound of targeted protein regulator and application thereof | 上海医药集团股份有限公司 | 2022-11-01 | — | — | CN | disclosed |
| US-10516111-B2 | Polymer/fullerene formations and their use in electronic/photonic devices | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2019-12-24 | — | — | US | disclosed |
| US-9831433-B2 | Conjugated polymers and devices incorporating the same | Raynergy Tek Incorporation (TW) | 2017-11-28 | — | — | US | disclosed |
| US-20160322575-A1 | POLYMER/FULLERENE FORMATIONS AND THEIR USE IN ELECTRONIC/PHOTONIC DEVICES | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2016-11-03 | — | — | US | disclosed |
| US-20160141499-A1 | CONJUGATED POLYMERS AND DEVICES INCORPORATING THE SAME | Raynergy Tek Incorporation (TW) | 2016-05-19 | — | — | US | disclosed |
| WO-2015096797-A1 | POLYMER/FULLERENE FORMATIONS AND THEIR USE IN ELECTRONIC/PHOTONIC DEVICES | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2015-07-02 | — | — | WO | disclosed |
| US-7838130-B2 | Aminodibenzofluorene derivative and organic electroluminescence device using the same | IDEMITSU KOSAN CO., LTD. (JP) | 2010-11-23 | — | — | US | disclosed |
| US-20090267491-A1 | AMINODIBENZOFLUORENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2009-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090267491-A1 | AMINODIBENZOFLUORENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME | L1CAM, DDC, LEF1 | TSHR 4740/4885THRB 4396/4885LMNA 516/4885 |
| US-20230365563-A1 | QUINAZOLINE COMPOUND AND APPLICATION THEREOF | KRAS, NRAS, BRAF | TSHR 4687/4885THRB 3677/4885LMNA 3525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.