Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.42 |
| ▸ | FDPS | P14324 | 3/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26106 | 1.00 | — | — | |
| SCHEMBL7574727 | 1.00 | TSHR (0.50) | TSHRTHRBLMNADNM1OPRM1 | |
| Hexane SCHEMBL17747414 | 1.00 | TSHR (0.50) | TSHRTHRBLMNADNM1OPRM1 | |
| Hexane SCHEMBL3754301 | 1.00 | TSHR (0.50) | TSHRTHRBLMNADNM1OPRM1 | |
| SCHEMBL16969849 | 1.00 | TSHR (0.50) | TSHRTHRBLMNADNM1OPRM1 | |
| SCHEMBL154425 | 1.00 | TSHR (0.50) | TSHRTHRBLMNADNM1OPRM1 | |
| SCHEMBL688498 | 1.00 | TSHR (0.50) | TSHRTHRBLMNADNM1OPRM1 | |
| Hexane SCHEMBL1525236 | 1.00 | TSHR (0.50) | TSHRTHRBLMNADNM1OPRM1 | |
| Heptane SCHEMBL15226631 | 1.00 | TSHR (0.50) | TSHRTHRBLMNADNM1OPRM1 | |
| SCHEMBL977939 | 1.00 | TSHR (0.50) | TSHRTHRBLMNADNM1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110028676-A1 | Molecular Actuators, and Methods of Use Thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2011-02-03 | — | — | US | disclosed |
| US-20100298590-A1 | Silole-based monomers and polymers for organic light-emitting diode devices | GEORGIA TECH RESEARCH CORPORATION (US) | 2010-11-25 | — | — | US | disclosed |
| EP-2235025-A1 | SILOLE-BASED MONOMERS AND POLYMERS FOR ORGANIC LIGHT-EMITTING DIODE DEVICES | Georgia Tech Research Corporation (US) | 2010-10-06 | — | — | EP | disclosed |
| US-7658868-B2 | Class of molecular actuators where bulk actuation mechanisms such as ion intercalation are enhanced by controllable single molecule conformational rearrangements offers promise in exhibiting large active strains at moderate stresses | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-02-09 | — | — | US | disclosed |
| WO-2009080796-A1 | SILOLE-BASED MONOMERS AND POLYMERS FOR ORGANIC LIGHT-EMITTING DIODE DEVICES | GEORGIA TECH RESEARCH CORPORATION (US) | 2009-07-02 | — | — | WO | disclosed |
| US-20070215839-A1 | Molecular actuators, and methods of use thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2007-09-20 | — | — | US | disclosed |
| US-7138075-B2 | Molecular actuators, and methods of use thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2006-11-21 | — | — | US | disclosed |
| US-20040007695-A1 | Molecular actuators, and methods of use thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2004-01-15 | — | — | US | disclosed |
| WO-2003101955-A2 | MOLECULAR ACTUATORS, AND METHODS OF USE THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2003-12-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070215839-A1 | Molecular actuators, and methods of use thereof | NOD2, PIEZO1, TPR | TSHR 3217/4885THRB 3312/4885LMNA 3835/4885 |
| US-20100298590-A1 | Silole-based monomers and polymers for organic light-emitting diode devices | CLTB, MAP1LC3B, MAP1LC3A | TSHR 4780/4885THRB 3941/4885LMNA 1205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.