Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | RAD52 | P43351 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.51 |
| ▸ | APEX1 | P27695 | 7/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.49 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13058122 | 0.84 | LMNA (0.57) | LMNAMAPTTP53NPC1APEX1 | |
| SCHEMBL1494800 | 0.83 | APEX1 (0.73) | LMNAMAPTTP53NPC1APEX1 | |
| SCHEMBL1495068 | 0.82 | APEX1 (0.64) | LMNAMAPTTP53NPC1APEX1 | |
| SCHEMBL3757276 | 0.82 | MEN1 (0.64) | LMNAMAPTTP53NPC1APEX1 | |
| SCHEMBL1494908 | 0.81 | LMNA (0.59) | LMNAMAPTTP53NPC1APEX1 | |
| SCHEMBL3800758 | 0.81 | LMNA (0.62) | LMNAMAPTTP53NPC1APEX1 | |
| SCHEMBL3746827 | 0.80 | LMNA (0.60) | LMNAMAPTTP53NPC1APEX1 | |
| SCHEMBL1494982 | 0.80 | LMNA (0.67) | LMNAMAPTTP53NPC1APEX1 | |
| SCHEMBL3753734 | 0.80 | APEX1 (0.69) | LMNAMAPTTP53RAD52NPC1 | |
| SCHEMBL13058120 | 0.80 | LMNA (0.57) | LMNAMAPTTP53NPC1APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100298370-A1 | BENZOTHIAZOLYL THIENOPYRIDINE DERIVATIVES AND USES THEREOF | RIMONYX PHARMACEUTICALS LTD. (IL) | 2010-11-25 | — | — | US | claimed |
| WO-2008020438-A2 | BENZOTHIAZOLYL THIENOPYRIDINE DERIVATIVES AND USES THEREOF | RIMONYX PHARMACEUTICALS LTD (IL) | 2008-02-21 | — | — | WO | claimed |
| US-20100298370-A1 | BENZOTHIAZOLYL THIENOPYRIDINE DERIVATIVES AND USES THEREOF | RIMONYX PHARMACEUTICALS LTD. (IL) | 2010-11-25 | — | — | US | disclosed |
| US-20100298370-A1 | BENZOTHIAZOLYL THIENOPYRIDINE DERIVATIVES AND USES THEREOF | RIMONYX PHARMACEUTICALS LTD. (IL) | 2010-11-25 | — | — | US | disclosed |
| US-20100298370-A1 | BENZOTHIAZOLYL THIENOPYRIDINE DERIVATIVES AND USES THEREOF | RIMONYX PHARMACEUTICALS LTD. (IL) | 2010-11-25 | — | — | US | disclosed |
| WO-2008020438-A2 | BENZOTHIAZOLYL THIENOPYRIDINE DERIVATIVES AND USES THEREOF | RIMONYX PHARMACEUTICALS LTD (IL) | 2008-02-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298370-A1 | BENZOTHIAZOLYL THIENOPYRIDINE DERIVATIVES AND USES THEREOF | HPSE, HDGF, HPGDS | LMNA 4715/4885MAPT 1611/4885TP53 847/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.