Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PLK1 | P53350 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1413702 | 0.88 | SMN1; SMN2 (0.66) | SMN1; SMN2CYP2C19CYP3A4TSHRPOLB | |
| SCHEMBL3758449 | 0.85 | THRB (0.44) | SMN1; SMN2CYP2C19CYP3A4TSHRPOLB | |
| SCHEMBL28642967 | 0.82 | SMN1; SMN2 (0.59) | SMN1; SMN2CYP2C19CYP3A4TSHRPOLB | |
| SCHEMBL380836 | 0.81 | CYP2C19 (0.58) | SMN1; SMN2CYP2C19CYP3A4TSHRPOLB | |
| SCHEMBL1958568 | 0.81 | CYP2C19 (0.58) | SMN1; SMN2CYP2C19CYP3A4TSHRPOLB | |
| SCHEMBL11511370 | 0.80 | SMN1; SMN2 (0.61) | SMN1; SMN2CYP2C19CYP3A4TSHRPOLB | |
| SCHEMBL3755582 | 0.80 | SMN1; SMN2 (0.61) | SMN1; SMN2CYP2C19CYP3A4TSHRPOLB | |
| SCHEMBL5852173 | 0.78 | SMN1; SMN2 (0.70) | SMN1; SMN2CYP2C19POLBRAB9AMAPT | |
| SCHEMBL4277318 | 0.78 | CYP3A4 (0.50) | CYP3A4TSHRCA1CA2ACHE | |
| SCHEMBL778838 | 0.78 | SMN1; SMN2 (0.69) | SMN1; SMN2CYP2C19CYP3A4TSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107573375-B | A kind of Memantine derivative and preparation method thereof | 成都苑东生物制药股份有限公司 | 2019-07-26 | — | — | CN | disclosed |
| CN-107573375-A | A kind of Memantine derivative and preparation method thereof | 成都苑东生物制药股份有限公司 | 2018-01-12 | — | — | CN | disclosed |
| US-20100298506-A1 | METHOD FOR PRODUCING AN AMINO GROUP-CONTAINING PHOSPHATE COMPOUND, AND A FLAME-RETARDANT RESIN AND FLAME-RETARDANT RESIN COMPOSITION | SHOWA HIGHPOLYMER CO., LTD. (JP) | 2010-11-25 | — | — | US | disclosed |
| CN-101617014-A | Flame-retardant adhesive composition, flexible copper-clad laminate and coverlay film | SHOWA HIGHPOLYMER | 2009-12-30 | — | — | CN | disclosed |
| CN-101460511-A | Method for producing amino group-containing phosphate ester compound, flame-retardant resin, and flame-retardant resin composition | SHOWA HIGHPOLYMER (JP) | 2009-06-17 | — | — | CN | disclosed |
| EP-2036911-A1 | PROCESS FOR PRODUCTION OF AMINATED PHOSPHORIC ACID ESTER COMPOUND, FLAME-RETARDANT RESIN, AND FLAME-RETARDANT RESIN COMPOSITION | SHOWA HIGHPOLYMER CO., LTD. (JP) | 2009-03-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298506-A1 | METHOD FOR PRODUCING AN AMINO GROUP-CONTAINING PHOSPHATE COMPOUND, AND A FLAME-RETARDANT RESIN AND FLAME-RETARDANT RESIN COMPOSITION | ATIC, GART, RPP30 | SMN1; SMN2 4067/4885CYP2C19 2840/4885CYP3A4 2190/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.