Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | CFTR | P13569 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.57 |
| ▸ | HPGD | P15428 | 6/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | PLK1 | P53350 | 1/20 | 0.55 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | FADS1 | O60427 | 2/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27744263 | 0.98 | ALDH1A1 (0.57) | ALDH1A1HSD17B10GAACFTRKDM4E | |
| Acetic Acid SCHEMBL28650473 | 0.94 | KDM4E (0.56) | ALDH1A1HSD17B10GAACFTRKDM4E | |
| SCHEMBL14227351 | 0.86 | PLK1 (0.55) | ALDH1A1HSD17B10GAACFTRKDM4E | |
| SCHEMBL31260535 | 0.86 | ALDH1A1 (0.53) | ALDH1A1HSD17B10GAACFTRKDM4E | |
| SCHEMBL2344909 | 0.84 | GAA (0.71) | ALDH1A1GAAPLK1 | |
| SCHEMBL5252014 | 0.83 | PLK1 (0.52) | ALDH1A1HSD17B10GAACFTRKDM4E | |
| SCHEMBL9254644 | 0.83 | ALDH1A1 (0.55) | ALDH1A1HSD17B10GAACFTRKDM4E | |
| SCHEMBL7653624 | 0.82 | KDM4E (0.47) | ALDH1A1HSD17B10GAACFTRKDM4E | |
| SCHEMBL9921278 | 0.82 | KDM4E (0.60) | ALDH1A1HSD17B10GAACFTRKDM4E | |
| SCHEMBL2299529 | 0.82 | PLK1 (0.50) | ALDH1A1HSD17B10GAACFTRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 593 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4646271-A1 | SUBSTITUTED SPIROCYCLIC-PYRROLOQUINAZOLINONES AND SPIROCYCLIC-PIPERIDINOQUINAZOLINONES | Mirati Therapeutics, Inc. (US) | 2025-11-12 | — | — | EP | claimed |
| CN-120079371-A | Oxygen vacancy-containing tungsten trioxide catalyst and preparation method and application thereof | 南京理工大学 | 2025-06-03 | — | — | CN | claimed |
| CN-118878468-A | Diamino pyrimidine compound containing phenyl nitrogen mustard fragment and preparation method and application thereof | 贵州大学 | 2024-11-01 | — | — | CN | claimed |
| WO-2024148150-A1 | SUBSTITUTED SPIROCYCLIC-PYRROLOQUINAZOLINONES AND SPIROCYCLIC-PIPERIDINOQUINAZOLINONES | Mirati Therapeutics, Inc. (US) | 2024-07-11 | — | — | WO | claimed |
| WO-2023127883-A1 | INDAZOLE COMPOUND AND PHARMACEUTICAL | 日本新薬株式会社 | 2023-07-06 | — | — | WO | claimed |
| CN-112142620-B | Synthetic method of 2-amino-3, 5-dichloro-N-methylbenzamide | 江西省科学院应用化学研究所 | 2023-03-31 | — | — | CN | claimed |
| CN-112142620-A | Synthetic method of 2-amino-3, 5-dichloro-N-methylbenzamide | 江西省科学院应用化学研究所 | 2020-12-29 | — | — | CN | claimed |
| CN-111454219-A | 5-trifluoromethyl pyrimidine derivative and preparation method and application thereof | 贵州大学 | 2020-07-28 | — | — | CN | claimed |
| CN-104744379-B | A kind of quianzolinones and its synthetic method | 三峡大学 | 2017-10-27 | — | — | CN | claimed |
| EP-2580207-B1 | NITROGEN CONTAINING HETEROARYL COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2017-09-27 | — | — | EP | claimed |
| CN-104557738-A | Green synthesis method of 4(3H)-quinazolinone | UNIV HUNAN | 2015-04-29 | — | — | CN | claimed |
| CN-104447580-A | Method for synthesizing quinazolone compounds | UNIV HUNAN | 2015-03-25 | — | — | CN | claimed |
| US-8703768-B2 | Nitrogen containing heteroaryl compounds | HOFFMANN-LA ROCHE INC. (US) | 2014-04-22 | — | — | US | claimed |
| US-8623866-B2 | — | — | 2014-01-07 | — | — | US | claimed |
| CN-103432077-A | Chidamide solid dispersion preparation | BEIJING GANHANG MEDICINE SCIENCE & TECHNOLOGY CO LTD | 2013-12-11 | — | — | CN | claimed |
| EP-2580207-A1 | NITROGEN CONTAINING HETEROARYL COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2013-04-17 | — | — | EP | claimed |
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | claimed |
| WO-2011154327-A1 | NITROGEN CONTAINING HETEROARYL COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2011-12-15 | — | — | WO | claimed |
| US-20110306589-A1 | NITROGEN CONTAINING HETEROARYL COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2011-12-15 | — | — | US | claimed |
| EP-1114047-B1 | AN IMPROVED PROCESS FOR THE PREPARATION OF THIAZOLIDINE-2,4-DIONE DERIVATIVES | REDDYS LAB LTD DR (IN) | 2003-03-19 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110306589-A1 | NITROGEN CONTAINING HETEROARYL COMPOUNDS | PDE10A, PDE3A, PDE2A | ALDH1A1 271/4885HSD17B10 88/4885GAA 963/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.