Toluene

Toluene

SCHEMBL3755843

CC(C)O.Cc1ccccc1.O=C1CCCCC1

nearest known ligand 0.42

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.42
TRIM24 O15164 2/20 0.42
TRIM33 Q9UPN9 2/20 0.42
LMNA P02545 1/20 0.42
TSHR P16473 1/20 0.42
ALOX12 P18054 1/20 0.42
ACHE P22303 1/20 0.42
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35
HTT P42858 1/20 0.35
KDM4E B2RXH2 5/20 0.35
KMT2A Q03164 4/20 0.35
MEN1 O00255 3/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C9 P11712 1/20 0.34
CHRNA1 P02708 1/20 0.34
CHRNG P07510 1/20 0.34
CHRNB1 P11230 1/20 0.34
CHRNB2 P17787 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
P-Xylene SCHEMBL28191408 0.93 CES2 (0.39) ALDH1A1TRIM24TRIM33LMNATSHR
O-Xylene SCHEMBL28191410 0.90 ALDH1A1 (0.34) ALDH1A1TRIM24TRIM33LMNATSHR
Cycloheptanone SCHEMBL28118482 0.90 TRIM24 (0.52) ALDH1A1TRIM24TRIM33LMNATSHR
Toluene SCHEMBL1635353 0.90 TRIM24 (0.52) ALDH1A1TRIM24TRIM33LMNATSHR
Toluene SCHEMBL27890798 0.90 TRIM24 (0.52) ALDH1A1TRIM24TRIM33LMNATSHR
P-Xylene SCHEMBL28222223 0.88 TRIM24 (0.50) ALDH1A1TRIM24TRIM33LMNATSHR
Toluene SCHEMBL28202304 0.88 TRIM24 (0.50) ALDH1A1TRIM24TRIM33LMNATSHR
Toluene SCHEMBL10011124 0.88 LMNA (0.55) ALDH1A1TRIM24TRIM33LMNATSHR
Toluene SCHEMBL4157178 0.87 ALDH1A1 (0.41) ALDH1A1TRIM24TRIM33LMNATSHR
P-Xylene SCHEMBL28185919 0.86 SMN1; SMN2 (0.36) ALDH1A1LMNAALOX12CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100302489-A1 LIQUID CRYSTAL LAYER FORMING INK COMPOSITION, AND OPTICAL FILM, POLARIZING FILM AND LIQUID CRYSTAL DISPLAY PRODUCED WITH THE INK COMPOSITION DAI NIPPON PRINTING CO., LTD. (JP) 2010-12-02 US disclosed
US-20090033834-A1 LIQUID CRYSTAL LAYER FORMING INK COMPOSITION, AND OPTICAL FILM, POLARIZING FILM AND LIQUID CRYSTAL DISPLAY PRODUCED WITH THE INK COMPOSITION DAI NIPPON PRINTING CO., LTD. (JP) 2009-02-05 US disclosed