Toluene

Toluene

SCHEMBL3756257

C=C(C)C(=O)O[SiH3].Cc1ccccc1

nearest known ligand 0.45

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.45
LMNA P02545 3/20 0.42
TSHR P16473 1/20 0.42
ALOX12 P18054 1/20 0.42
ACHE P22303 1/20 0.42
CES2 O00748 2/20 0.39
CES1 P23141 2/20 0.39
ALDH1A1 P00352 5/20 0.39
MAPT P10636 2/20 0.39
KDM4E B2RXH2 1/20 0.38
NPC1 O15118 3/20 0.36
RAB9A P51151 3/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
HPGD P15428 1/20 0.35
SMN1; SMN2 Q16637 3/20 0.34
AKR1C3 P42330 1/20 0.34
TSPO P30536 1/20 0.33
POLB P06746 1/20 0.33
APEX1 P27695 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL8157940 0.82 ALDH1A1 (0.60) ELANELMNATSHRALOX12ACHE
Toluene SCHEMBL28822193 0.81 LMNA (0.52) ELANELMNATSHRALOX12ACHE
Toluene SCHEMBL28087905 0.79 THRB (0.52) ELANELMNATSHRALOX12ACHE
Toluene SCHEMBL10539493 0.79 LMNA (0.55) ELANELMNATSHRALOX12ACHE
Toluene SCHEMBL1692174 0.79 LMNA (0.55) ELANELMNATSHRALOX12ACHE
Bicarbonate SCHEMBL28141965 0.79 ALDH1A1 (0.50) ELANETSHRALDH1A1POLBAPEX1
SCHEMBL49593 0.78
Toluene SCHEMBL8927127 0.78 ELANE (0.42) ELANELMNATSHRALOX12ACHE
Toluene SCHEMBL28163623 0.78 ELANE (0.42) ELANELMNATSHRALOX12ACHE
Methacrylic Acid SCHEMBL5057349 0.77 ALDH1A1 (0.48) ELANETSHRALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7838916-B2 Thin-film transistor, electronic circuit, display unit, and electronic device SEIKO EPSON CORPORATION (JP) 2010-11-23 US disclosed
US-20070126002-A1 THIN-FILM TRANSISTOR, ELECTRONIC CIRCUIT, DISPLAY UNIT, AND ELECTRONIC DEVICE SEIKO EPSON CORPORATION (JP) 2007-06-07 US disclosed