SCHEMBL3756384

SCHEMBL3756384

Cc1ccc(OP(=O)(OCl)OCl)cc1

nearest known ligand 0.75

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.75
TSHR P16473 2/20 0.75
ALDH1A1 P00352 2/20 0.45
MAPK1 P28482 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
MEN1 O00255 6/20 0.42
KMT2A Q03164 6/20 0.42
LMNA P02545 3/20 0.42
MAPT P10636 1/20 0.42
NPSR1 Q6W5P4 1/20 0.41
ACHE P22303 1/20 0.41
HSP90AA1 P07900 1/20 0.40
GAA P10253 1/20 0.40
HPGD P15428 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2776814 0.96 CYP3A4 (0.75) CYP3A4TSHRALDH1A1MAPK1TDP1
SCHEMBL5851924 0.88 CYP3A4 (0.64) CYP3A4TSHRALDH1A1TDP1MEN1
SCHEMBL131412 0.86 TSHR (1.00) CYP3A4TSHRALDH1A1MAPK1TDP1
SCHEMBL27393883 0.86 TSHR (1.00) CYP3A4TSHRALDH1A1MAPK1TDP1
SCHEMBL27371282 0.86 TSHR (1.00) CYP3A4TSHRALDH1A1MAPK1TDP1
SCHEMBL10336991 0.86 TSHR (1.00) CYP3A4TSHRALDH1A1MAPK1TDP1
SCHEMBL21582 0.86 TSHR (1.00) CYP3A4TSHRALDH1A1MAPK1TDP1
SCHEMBL28869386 0.84 TSHR (0.95) CYP3A4TSHRALDH1A1MAPK1TDP1
SCHEMBL8331868 0.84 TSHR (0.95) CYP3A4TSHRALDH1A1MAPK1TDP1
SCHEMBL9785893 0.84 CYP3A4 (0.95) CYP3A4TSHRALDH1A1MAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113429770-A Preparation method of efficient flame-retardant modified unsaturated polyester resin 中国科学技术大学 2021-09-24 CN claimed
CN-113336898-A Preparation method of styrene-free flame-retardant unsaturated polyester resin 中国科学技术大学 2021-09-03 CN claimed
CN-102786694-B Biphenol polyphosphate fire retardant and preparation method and application thereof UNIV GUIZHOU NORMAL 2014-03-12 CN claimed
CN-113429770-A Preparation method of efficient flame-retardant modified unsaturated polyester resin 中国科学技术大学 2021-09-24 CN disclosed
CN-113354822-A Halogen-containing polymeric organic phosphate flame retardant and preparation method and application thereof 中国科学技术大学 2021-09-07 CN disclosed
CN-113336898-A Preparation method of styrene-free flame-retardant unsaturated polyester resin 中国科学技术大学 2021-09-03 CN disclosed
EP-1928475-B1 ANTIVIRAL PHOSPHORAMIDATES OF 4'-C-AZIDO-SUBSTITUTED PRONUCLEOTIDES RIBOSCIENCE LLC (US) 2018-05-23 EP disclosed
CN-105339473-B Multifunctional lubricant composition 株式会社ADEKA 2018-01-02 CN disclosed
CN-105339473-A Polyfunctional lubricant composition ADEKA CORP 2016-02-17 CN disclosed
CN-102786694-B Biphenol polyphosphate fire retardant and preparation method and application thereof UNIV GUIZHOU NORMAL 2014-03-12 CN disclosed
CN-102643437-B Polyphosphate fire retardant with diphenol structure and preparation method for same using interfacial polymerization method UNIV NANJING NORMAL 2014-01-22 CN disclosed
CN-102643437-A Polyphosphate fire retardant with diphenol structure and preparation method for same using interfacial polymerization method UNIV NANJING NORMAL 2012-08-22 CN disclosed
US-20100298506-A1 METHOD FOR PRODUCING AN AMINO GROUP-CONTAINING PHOSPHATE COMPOUND, AND A FLAME-RETARDANT RESIN AND FLAME-RETARDANT RESIN COMPOSITION SHOWA HIGHPOLYMER CO., LTD. (JP) 2010-11-25 US disclosed
US-7608599-B2 Antiviral phosphoramidates ROCHE PALO ALTO LLC (US) 2009-10-27 US disclosed
EP-2036911-A1 PROCESS FOR PRODUCTION OF AMINATED PHOSPHORIC ACID ESTER COMPOUND, FLAME-RETARDANT RESIN, AND FLAME-RETARDANT RESIN COMPOSITION SHOWA HIGHPOLYMER CO., LTD. (JP) 2009-03-18 EP disclosed
US-20070042988-A1 Antiviral phosphoramidates ROCHE PALO ALTO LLC 2007-02-22 US disclosed
US-4028481-A ACTIVATED TITANIUM TRICHLORIDE AND AN ORGANOALUMINUM COMPOUND MITSUI TOATSU CHEMICALS, INCORPORATED (JA) 1977-06-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070042988-A1 Antiviral phosphoramidates RPP30, RNASE1, ADORA2B CYP3A4 2407/4885TSHR 1539/4885ALDH1A1 1942/4885
US-20100298506-A1 METHOD FOR PRODUCING AN AMINO GROUP-CONTAINING PHOSPHATE COMPOUND, AND A FLAME-RETARDANT RESIN AND FLAME-RETARDANT RESIN COMPOSITION ATIC, GART, RPP30 CYP3A4 2190/4885TSHR 2372/4885ALDH1A1 2459/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.