Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL319535 | 1.00 | TSHR (0.39) | TSHRALDH1A1TDP1 | |
| SCHEMBL1002671 | 0.97 | — | — | |
| SCHEMBL1002630 | 0.89 | — | — | |
| SCHEMBL55582 | 0.77 | — | — | |
| SCHEMBL12311052 | 0.76 | — | — | |
| SCHEMBL7895514 | 0.76 | THRB (0.44) | TSHR | |
| SCHEMBL1054429 | 0.76 | THRB (0.44) | TSHR | |
| SCHEMBL8598989 | 0.76 | THRB (0.44) | TSHR | |
| SCHEMBL6891701 | 0.76 | THRB (0.44) | TSHR | |
| SCHEMBL5200527 | 0.76 | THRB (0.44) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1560880-B1 | TYRE BELT BASED ON AN INORGANIC FILLER AND A POLYSULPHIDE SILANE | MICHELIN & CIE (FR) | 2014-08-27 | — | — | EP | disclosed |
| US-8461369-B2 | Preparation of organomonoalkoxy (or monohydroxy) silanes from alkoxysilanes/organometallic compounds | RHODIA OPERATIONS (FR) | 2013-06-11 | — | — | US | disclosed |
| EP-1392769-B1 | TYRE AND RUNNING TREAD COMPRISING AS COUPLING AGENT A BIS-ALKOXYSILANE TETRASULPHIDE | MICHELIN SOC TECH (FR) | 2012-01-25 | — | — | EP | disclosed |
| EP-1377602-B1 | USE OF ORGANOSILOXANE POLYSULPHIDES IN DIENIC ELASTOMERS COMPOSITIONS | RHODIA CHIMIE SA (FR) | 2011-07-13 | — | — | EP | disclosed |
| US-20100185005-A1 | PREPARATION OF ORGANOMONOALKOXY (OR MONOHYDROXY) SILANES FROM ALKOXYSILANES/ORGANOMETALLIC COMPOUNDS | RHODIA OPERATIONS (FR) | 2010-07-22 | — | — | US | disclosed |
| EP-2134728-A2 | METHOD FOR PROCESSING ALKOXYSILANES USING AN ORGANOMETALLIC COMPOUND, IN PARTICULAR FOR PREPARING ORGANOMONOALKOXY(OR MONOHYDROXY)SILANES | Rhodia Opérations (FR) | 2009-12-23 | — | — | EP | disclosed |
| WO-2008110490-A2 | METHOD FOR PROCESSING ALKOXYSILANES USING AN ORGANOMETALLIC COMPOUND, IN PARTICULAR FOR PREPARING ORGANOMONOALKOXY(OR MONOHYDROXY)SILANES | RHODIA OPERATIONS (FR) | 2008-09-18 | — | — | WO | disclosed |
| EP-1423459-B1 | DIENE RUBBER COMPOSITION FOR TYRES COMPRISING A SPECIFIC SILICON AS A REINFORCING FILLER | MICHELIN SOC TECH (FR) | 2008-02-27 | — | — | EP | disclosed |
| WO-2008006853-A2 | PROCESS FOR PREPARING FUNCTIONALIZED - ESPECIALLY HALOGENATED - ORGANOMONOALKOXYSILANES | RHODIA OPERATIONS (FR) | 2008-01-17 | — | — | WO | disclosed |
| US-7250463-B2 | Diene rubber composition for tire comprising a specific silica as reinforcing filler | MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) | 2007-07-31 | — | — | US | disclosed |
| EP-1423459-A1 | DIENE RUBBER COMPOSITION FOR TYRES COMPRISING A SPECIFIC SILICON AS A REINFORCING FILLER | Société de Technologie Michelin (FR) | 2004-06-02 | — | — | EP | disclosed |
| WO-2004033548-A1 | TYRE BELT BASED ON AN INORGANIC FILLER AND A POLYSULPHIDE SILANE | SOCIETE DE TECHNOLOGIE MICHELIN (FR) | 2004-04-22 | — | — | WO | disclosed |
| EP-1392769-A1 | TYRE AND RUNNING TREAD COMPRISING AS COUPLING AGENT A BIS-ALKOXYSILANE TETRASULPHIDE | Société de Technologie Michelin (FR) | 2004-03-03 | — | — | EP | disclosed |
| EP-1377602-A1 | POLYSULPHIDE ORGANOSILOXANES WHICH CAN BE USED AS COUPLING AGENTS, ELASTOMER COMPOSITIONS CONTAINING SAME AND ELASTOMER ARTICLES PREPARED FROM SAID COMPOSITIONS | RHODIA CHIMIE (FR) | 2004-01-07 | — | — | EP | disclosed |
| WO-2003016387-A1 | DIENE RUBBER COMPOSITION FOR TYRES COMPRISING A SPECIFIC SILICON AS A REINFORCING FILLER | SOCIETE DE TECHNOLOGIE MICHELIN (FR) | 2003-02-27 | — | — | WO | disclosed |
| WO-2002083719-A1 | POLYSULPHIDE ORGANOSILOXANES WHICH CAN BE USED AS COUPLING AGENTS, ELASTOMER COMPOSITIONS CONTAINING SAME AND ELASTOMER ARTICLES PREPARED FROM SAID COMPOSITIONS | RHODIA CHIMIE (FR) | 2002-10-24 | — | — | WO | disclosed |
| WO-2002083782-A1 | TYRE AND RUNNING TREAD COMPRISING AS COUPLING AGENT A BIS-ALKOXYSILANE TETRASULPHIDE | SOCIETE DE TECHNOLOGIE MICHELIN (FR) | 2002-10-24 | — | — | WO | disclosed |
| EP-0212058-B1 | N-SILYLPROPYL-N'-ACYL UREAS AND PREPARATION PROCESS | Degussa Aktiengesellschaft (DE) | 1990-01-31 | — | — | EP | disclosed |
| US-4697009-A | N-silylpropyl-N'-acyl-ureas and process for their production | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1987-09-29 | — | — | US | disclosed |
| EP-0212058-A2 | N-silylpropyl-N'-acyl ureas and preparation process | Degussa Aktiengesellschaft (DE) | 1987-03-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100185005-A1 | PREPARATION OF ORGANOMONOALKOXY (OR MONOHYDROXY) SILANES FROM ALKOXYSILANES/ORGANOMETALLIC COMPOUNDS | MSMO1, HAO2, HAAO | TSHR 3765/4885ALDH1A1 1136/4885TDP1 4748/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.