Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL375641 | 1.00 | TSHR (0.39) | TSHRALDH1A1TDP1 | |
| SCHEMBL1002671 | 0.97 | — | — | |
| SCHEMBL1002630 | 0.89 | — | — | |
| SCHEMBL55582 | 0.77 | — | — | |
| SCHEMBL12311052 | 0.76 | — | — | |
| SCHEMBL7895514 | 0.76 | THRB (0.44) | TSHR | |
| SCHEMBL1054429 | 0.76 | THRB (0.44) | TSHR | |
| SCHEMBL8598989 | 0.76 | THRB (0.44) | TSHR | |
| SCHEMBL6891701 | 0.76 | THRB (0.44) | TSHR | |
| SCHEMBL5200527 | 0.76 | THRB (0.44) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10221200-B2 | Quaternary amino alcohol functional organosilicon compounds, composition containing the latter and their production and use | EVONIK DEGUSSA GMBH (DE) | 2019-03-05 | — | — | US | disclosed |
| US-9796738-B2 | Quaternary amino alcohol functional organosilicon compounds, composition containing the latter and their production and use | EVONIK DEGUSSA GMBH (DE) | 2017-10-24 | — | — | US | disclosed |
| US-20170233416-A1 | Quaternary amino alcohol functional organosilicon compounds, composition containing the latter and their production and use | EVONIK DEGUSSA GMBH (DE) | 2017-08-17 | — | — | US | disclosed |
| EP-2590988-B1 | QUATERNARY AMINO ALCOHOL FUNCTIONAL ORGANOSILICON COMPOUNDS, COMPOSITION CONTAINING THE LATTER AND THEIR PRODUCTION AND USE | EVONIK DEGUSSA GMBH (DE) | 2017-03-01 | — | — | EP | disclosed |
| EP-2421874-B1 | COMPOSITION CONTAINING QUATERNARY AMINO-FUNCTIONAL ORGANOSILICON COMPOUNDS AND PRODUCTION AND USE THEREOF | EVONIK DEGUSSA GMBH (DE) | 2015-09-30 | — | — | EP | disclosed |
| US-8979996-B2 | Composition containing quaternary amino-functional organosilicon compunds and production and use thereof | EVONIK DEGUSSA GMBH (DE) | 2015-03-17 | — | — | US | disclosed |
| US-8980960-B2 | Methods for producing a dispersion containing silicon dioxide particles and cationization agent | EVONIK DEGUSSA GMBH (DE) | 2015-03-17 | — | — | US | disclosed |
| US-20140208981-A1 | COMPOSITION CONTAINING QUATERNARY AMINO-FUNCTIONAL ORGANOSILICON COMPOUNDS AND PRODUCTION AND USE THEREOF | EVONIK DEGUSSA GMBH (DE) | 2014-07-31 | — | — | US | disclosed |
| US-8747541-B2 | Dispersion containing silica particles surface-modified with quaternary, aminofunctional organosilicon compounds | EVONIK DEGUSSA GMBH (DE) | 2014-06-10 | — | — | US | disclosed |
| US-8728225-B2 | Composition containing quaternary amino-functional organosilicon compounds and production and use thereof | EVONIK DEGUSSA GMBH (DE) | 2014-05-20 | — | — | US | disclosed |
| US-20130167754-A1 | QUATERNARY AMINO ALCOHOL FUNCTIONAL ORGANOSILICON COMPOUNDS, COMPOSITION CONTAINING THE LATTER AND THEIR PRODUCTION AND USE | EVONIK DEGUSSA GMBH (DE) | 2013-07-04 | — | — | US | disclosed |
| EP-2590988-A2 | QUATERNARY AMINO ALCOHOL FUNCTIONAL ORGANOSILICON COMPOUNDS, COMPOSITION CONTAINING THE LATTER AND THEIR PRODUCTION AND USE | Evonik Degussa GmbH (DE) | 2013-05-15 | — | — | EP | disclosed |
| EP-2590759-A1 | METHODS FOR PRODUCING A DISPERSION CONTAINING SILICON DIOXIDE PARTICLES AND CATIONIZATION AGENT | Evonik Degussa GmbH (DE) | 2013-05-15 | — | — | EP | disclosed |
| US-20130040078-A1 | METHODS FOR PRODUCING A DISPERSION CONTAINING SILICON DIOXIDE PARTICLES AND CATIONIZATION AGENT | EVONIK DEGUSSA GMBH (DE) | 2013-02-14 | — | — | US | disclosed |
| EP-2421921-A1 | DISPERSION CONTAINING SILICA PARTICLES SURFACE-MODIFIED WITH QUATERNARY, AMINOFUNCTIONAL ORGANOSILICON COMPOUNDS | Evonik Degussa GmbH (DE) | 2012-02-29 | — | — | EP | disclosed |
| US-20120037040-A1 | COMPOSITION CONTAINING QUATERNARY AMINO-FUNCTIONAL ORGANOSILICON COMPOUNDS AND PRODUCTION AND USE THEREOF | EVONIK DEGUSSA GMBH (DE) | 2012-02-16 | — | — | US | disclosed |
| WO-2012004044-A1 | METHODS FOR PRODUCING A DISPERSION CONTAINING SILICON DIOXIDE PARTICLES AND CATIONIZATION AGENT | EVONIK DEGUSSA GMBH (DE) | 2012-01-12 | — | — | WO | disclosed |
| WO-2012004082-A2 | QUATERNARY AMINO ALCOHOL FUNCTIONAL ORGANOSILICON COMPOUNDS, COMPOSITION CONTAINING THE LATTER AND THEIR PRODUCTION AND USE | EVONIK DEGUSSA GMBH (DE) | 2012-01-12 | — | — | WO | disclosed |
| US-20120006228-A1 | DISPERSION CONTAINING SILICA PARTICLES SURFACE-MODIFIED WITH QUATERNARY, AMINOFUNCTIONAL ORGANOSILICON COMPOUNDS | EVONIK DEGUSSA GMBH (DE) | 2012-01-12 | — | — | US | disclosed |
| WO-2010121878-A1 | DISPERSION CONTAINING SILICA PARTICLES SURFACE-MODIFIED WITH QUATERNARY, AMINOFUNCTIONAL ORGANOSILICON COMPOUNDS | EVONIK DEGUSSA GMBH (DE) | 2010-10-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130167754-A1 | QUATERNARY AMINO ALCOHOL FUNCTIONAL ORGANOSILICON COMPOUNDS, COMPOSITION CONTAINING THE LATTER AND THEIR PRODUCTION AND USE | BCAT2, BCAT1, ADH5 | TSHR 4879/4885ALDH1A1 273/4885TDP1 1226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.