Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.72 |
| ▸ | MEN1 | O00255 | 6/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.72 |
| ▸ | RAB9A | P51151 | 3/20 | 0.72 |
| ▸ | LMNA | P02545 | 2/20 | 0.72 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.72 |
| ▸ | NPC1 | O15118 | 2/20 | 0.72 |
| ▸ | EGFR | P00533 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | RAD52 | P43351 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13909079 | 0.96 | MAPT (0.69) | MAPTMEN1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL11601873 | 0.94 | MAPT (0.64) | MAPTMEN1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL375688 | 0.90 | LMNA (0.87) | MAPTMEN1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL28768879 | 0.88 | MAPT (0.58) | MAPTMEN1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL10727142 | 0.84 | MAPT (0.52) | MAPTMEN1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL13135364 | 0.84 | LMNA (0.77) | MAPTMEN1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL13370284 | 0.84 | MEN1 (1.00) | MAPTMEN1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL11605189 | 0.83 | MAPT (0.55) | MAPTMEN1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL31218597 | 0.83 | MAPT (0.51) | MAPTMEN1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL15603989 | 0.83 | MAPT (0.51) | MAPTMEN1KMT2AMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116574020-A | Preparation and application of long-term stable silicone hydrogel contact lens colorant | 华诺森(湖北)光学有限公司 | 2023-08-11 | — | — | CN | claimed |
| CN-101090979-A | Probes, libraries and kits for analysis of mixtures of nucleic acids and methods for constructing the same | EXIQON AS (DK) | 2007-12-19 | — | — | CN | claimed |
| CN-116574020-A | Preparation and application of long-term stable silicone hydrogel contact lens colorant | 华诺森(湖北)光学有限公司 | 2023-08-11 | — | — | CN | disclosed |
| CN-116574020-A | Preparation and application of long-term stable silicone hydrogel contact lens colorant | 华诺森(湖北)光学有限公司 | 2023-08-11 | — | — | CN | disclosed |
| CN-1961081-B | Methods for quantification of microRNA and small interfering RNA | EXIQON AS | 2012-09-05 | — | — | CN | disclosed |
| CN-101090979-A | Probes, libraries and kits for analysis of mixtures of nucleic acids and methods for constructing the same | EXIQON AS (DK) | 2007-12-19 | — | — | CN | disclosed |
| EP-1556325-A4 | ANTHRAQUINONE QUENCHER DYES, THEIR METHODS OF PREPARATION AND USE | INTEGRATED DNA TECH INC (US) | 2007-09-19 | — | — | EP | disclosed |
| EP-1556325-A1 | ANTHRAQUINONE QUENCHER DYES, THEIR METHODS OF PREPARATION AND USE | Untegrated DNA Technologies, Inc. (US) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004026804-A1 | ANTHRAQUINONE QUENCHER DYES, THEIR METHODS OF PREPARATION AND USE | INTEGRATED DNA TECHNOLOGIES, INC. (US) | 2004-04-01 | — | — | WO | disclosed |
| US-20030203975-A1 | Anti-cancer agents | BTG INTERNATIONAL LIMITED (GB) | 2003-10-30 | — | — | US | disclosed |
| US-5663024-A | Liquid toners with hydrocarbon solvents | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-09-02 | — | — | US | disclosed |
| US-5530053-A | ELECTROSTATIC TONERS COMPRISING POLYMERIC DYES CONTAINING FLUORINATED MACROMERS COMPLEXED WITH A METAL CHARGE CONTROLLER; ANTIAGGLOMERANTS; QUICK-DRYING; TRANSFERABILITY; NON-FLAMMABLE; ELECTROGRAPHY | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030203975-A1 | Anti-cancer agents | TOP2B, TOP2A, TOP1 | MAPT 4879/4885MEN1 3787/4885KMT2A 3724/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.