Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.69 |
| ▸ | RAB9A | P51151 | 3/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.69 |
| ▸ | NPC1 | O15118 | 2/20 | 0.69 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
| ▸ | FGB | P02675 | 1/20 | 0.47 |
| ▸ | MMP14 | P50281 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5553577 | 0.96 | MAPT (0.72) | MAPTMAPK1L3MBTL1RAB9AMEN1 | |
| SCHEMBL11601873 | 0.95 | MAPT (0.64) | MAPTMAPK1L3MBTL1RAB9AMEN1 | |
| SCHEMBL375688 | 0.88 | LMNA (0.87) | MAPTMAPK1L3MBTL1RAB9AMEN1 | |
| SCHEMBL28768879 | 0.87 | MAPT (0.58) | MAPTMAPK1L3MBTL1RAB9AMEN1 | |
| SCHEMBL9309333 | 0.85 | MAPT (0.51) | MAPTMAPK1L3MBTL1RAB9AMEN1 | |
| SCHEMBL9309180 | 0.82 | MAPT (0.49) | MAPTMAPK1L3MBTL1RAB9AMEN1 | |
| SCHEMBL13370284 | 0.82 | MEN1 (1.00) | MAPTMAPK1L3MBTL1RAB9AMEN1 | |
| SCHEMBL13135364 | 0.82 | LMNA (0.77) | MAPTMAPK1L3MBTL1RAB9AMEN1 | |
| SCHEMBL375206 | 0.81 | TDP1 (0.52) | MAPTMAPK1L3MBTL1RAB9AMEN1 | |
| SCHEMBL9308563 | 0.81 | MAPT (0.48) | MAPTMAPK1L3MBTL1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7504495-B2 | Quencher compositions comprising anthraquinone moieties | EXIQON A/S (DK) | 2009-03-17 | — | — | US | disclosed |
| EP-1538154-B1 | Quencher composition comprising anthraquinone moieties | EXIQON AS (DK) | 2008-12-31 | — | — | EP | disclosed |