Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.74 |
| ▸ | USP2 | O75604 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.58 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.55 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6446137 | 0.85 | LMNA (0.69) | LMNATSHRP2RX7MAPTTP53 | |
| SCHEMBL3761561 | 0.82 | CXCR4 (0.64) | LMNAUSP2TSHRALOX15NPSR1 | |
| Hydrochloric Acid SCHEMBL8021990 | 0.81 | P2RX7 (0.58) | LMNAUSP2TSHRALOX15P2RX7 | |
| SCHEMBL18731438 | 0.81 | LMNA (0.53) | LMNAUSP2TSHRP2RX7MAPT | |
| SCHEMBL3400537 | 0.80 | CXCR4 (0.66) | LMNAUSP2TSHRALOX15NPSR1 | |
| SCHEMBL18732121 | 0.78 | LMNA (0.51) | LMNAALOX15P2RX7NPSR1MAPT | |
| SCHEMBL10219927 | 0.78 | TLR9 (0.53) | LMNAUSP2TSHRNPSR1MAPK1 | |
| SCHEMBL5547083 | 0.77 | KMT2A (0.56) | LMNAUSP2TSHRALOX15NPSR1 | |
| SCHEMBL2330274 | 0.77 | LMNA (0.69) | LMNATSHRP2RX7TP53RAB9A | |
| SCHEMBL229041 | 0.77 | POLB (0.67) | LMNATSHRALOX15NPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100297038-A1 | Benzimidazole Derivatives And Their Use As Cooling Agents | GIVAUDAN S.A. (CH) | 2010-11-25 | — | — | US | claimed |
| US-20100297038-A1 | Benzimidazole Derivatives And Their Use As Cooling Agents | GIVAUDAN S.A. (CH) | 2010-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100297038-A1 | Benzimidazole Derivatives And Their Use As Cooling Agents | OR10J3, H1-3, ORC3 | LMNA 1041/4885USP2 3760/4885TSHR 1643/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.