Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3746513 | 0.79 | MEN1 (0.32) | KMT2ACYP1A2CYP2C19CYP2C9MEN1 | |
| SCHEMBL3748475 | 0.77 | ALDH1A1 (0.33) | LMNAKMT2ACYP1A2CYP2C19CYP2C9 | |
| SCHEMBL26103877 | 0.76 | MEN1 (0.33) | KMT2ACYP1A2CYP2C19CYP2C9MEN1 | |
| SCHEMBL25907567 | 0.73 | CYP1A2 (0.39) | LMNAKMT2ACYP1A2CYP2C19CYP2C9 | |
| SCHEMBL25448854 | 0.73 | CYP1A2 (0.37) | LMNANPC1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL1027187 | 0.72 | MPO (0.32) | KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL3759353 | 0.72 | MEN1 (0.34) | KMT2ACYP1A2CYP2C19CYP2C9MEN1 | |
| SCHEMBL3761246 | 0.71 | MEN1 (0.32) | KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL31415034 | 0.71 | MEN1 (0.31) | KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL31415033 | 0.71 | MEN1 (0.31) | KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100298141-A1 | SUBSTITUTED PYRIDINE N-OXIDE HERBICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-11-25 | — | — | US | disclosed |
| EP-2120939-A2 | SUBSTITUTED PYRIDINE N-OXIDE HERBICIDES | E. I. Du Pont de Nemours and Company (US) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008100426-A2 | SUBSTITUTED PYRIDINE N-OXIDE HERBICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-08-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298141-A1 | SUBSTITUTED PYRIDINE N-OXIDE HERBICIDES | CYP3A7, CYP2W1, CBR3 | LMNA 4752/4885RAB9A 3000/4885NPC1 4368/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.