SCHEMBL9010837

SCHEMBL9010837

Nn1cnc2c(=O)nc[nH]c21

nearest known ligand 0.35

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.35
THRB P10828 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
KDM4E B2RXH2 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
PARP1 P09874 1/20 0.33
DUSP3 P51452 1/20 0.31
PTPN5 P54829 1/20 0.31
PTPN11 Q06124 1/20 0.31
HPRT1 P00492 1/20 0.31
HSD17B10 Q99714 1/20 0.31
PNP P00491 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7037922 0.80 ALDH1A1 (0.36) ALDH1A1MEN1KMT2AKDM4ETDP1
SCHEMBL28147771 0.78 ALDH1A1 (0.35) ALDH1A1MEN1KMT2AKDM4ETDP1
SCHEMBL612167 0.77 ALDH1A1 (0.34) ALDH1A1MEN1KMT2AKDM4ETDP1
SCHEMBL28004456 0.77 ALDH1A1 (0.34) ALDH1A1MEN1KMT2AKDM4ETDP1
SCHEMBL28004546 0.77 ALDH1A1 (0.34) ALDH1A1MEN1KMT2AKDM4ETDP1
SCHEMBL7168417 0.77 ALDH1A1 (0.34) ALDH1A1MEN1KMT2AKDM4ETDP1
SCHEMBL4404534 0.77 ALDH1A1 (0.34) ALDH1A1MEN1KMT2AKDM4ETDP1
SCHEMBL2639252 0.77 ALDH1A1 (0.37) ALDH1A1MEN1KMT2AKDM4ETDP1
SCHEMBL5523925 0.73 DUSP3 (0.38) ALDH1A1MEN1KMT2AKDM4ETDP1
SCHEMBL28275704 0.73 ALDH1A1 (0.48) ALDH1A1KDM4ETDP1HPRT1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118146607-A Broadband high-reflectivity anhydrous hypoxanthine film, and preparation method and application thereof 北京理工大学 2024-06-07 CN claimed
CN-118146607-A Broadband high-reflectivity anhydrous hypoxanthine film, and preparation method and application thereof 北京理工大学 2024-06-07 CN disclosed
CN-116482372-A Kit for quantitatively detecting homocysteine concentration based on time-resolved fluorescence dry immunochromatography and detection method thereof 广州达安基因股份有限公司 2023-07-25 CN disclosed
US-20220003771-A1 METHODS OF DETECTING A POLYPEPTIDE HAVING ANAPLASTIC LYMPHOMA KINASE ACTIVITY IN KIDNEY CANCER CELL SIGNALING TECHNOLOGY, INC. (US) 2022-01-06 US disclosed
CN-110520443-A FGF21 analog antibody and application thereof NOVARTIS AG 2019-11-29 CN disclosed
CN-110431152-A Anti- GITR antibody and its application method RINAT NEUROSCIENCE CORP 2019-11-08 CN disclosed
CN-110133251-A Purify aflatoxin-cyclopiazonic acid immunosorbent and immune affinity column 中国农业科学院油料作物研究所 2019-08-16 CN disclosed
CN-110133249-A Purify aflatoxin, cyclopiazonic acid, ochratoxin A and zearalenone immunosorbent and immune affinity column 中国农业科学院油料作物研究所 2019-08-16 CN disclosed
CN-110133250-A Purify aflatoxin, sterigmatocystin, cyclopiazonic acid immunosorbent and compound affinity column 中国农业科学院油料作物研究所 2019-08-16 CN disclosed
CN-106977600-B Purify fumonisin B1, aflatoxin, ochratoxin A, zearalenone immunosorbent and compound affinity column 中国农业科学院油料作物研究所 2019-08-13 CN disclosed
US-5030565-A Polypeptide-induced monoclonal receptors to protein ligands SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) 1991-07-09 US disclosed
EP-0354808-A2 Polypeptide-induced monoclonal receptors to protein ligands PROGENX, INC. (US) 1990-02-14 EP disclosed
WO-1988008135-A1 HUMAN MONOCLONAL ANTIBODIES BINDING DETERMINANTS OF GRAM NEGATIVE BACTERIA XOMA CORPORATION (US) 1988-10-20 WO disclosed
EP-0232871-A2 Human monoclonal antibody, hybridoma producing the same and its use Yoshitomi Pharmaceutical Industries, Ltd. (JP) 1987-08-19 EP disclosed
EP-0152477-A4 POLYPEPTIDE-INDUCED MONOCLONAL ANTIBODIES TO ONCOPROTEINS. SCRIPPS CLINIC RES (US) 1987-04-16 EP disclosed
EP-0210029-A2 Monoclonal antibodies to human plasma prekallikrein and methods of preparing and using same Temple University of the Commonwealth System of Higher Education (US) 1987-01-28 EP disclosed
WO-1985004653-A1 ANTIBODIES TO HUMAN INTERLEUKIN-2 INDUCED BY SYNTHETIC POLYPEPTIDES SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) 1985-10-24 WO disclosed
EP-0157643-A2 Antibodies to human interleukin-2 induced by synthetic polypeptides SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) 1985-10-09 EP disclosed
EP-0152477-A1 POLYPEPTIDE-INDUCED MONOCLONAL ANTIBODIES TO ONCOPROTEINS. SCRIPPS CLINIC RES (US) 1985-08-28 EP disclosed
WO-1985000807-A1 POLYPEPTIDE-INDUCED MONOCLONAL ANTIBODIES TO ONCOPROTEINS SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) 1985-02-28 WO disclosed