SCHEMBL4404534

SCHEMBL4404534

O=c1nc[nH]c2c1ncn2[SeH]

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
KDM4E B2RXH2 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
DUSP3 P51452 1/20 0.31
PTPN5 P54829 1/20 0.31
PTPN11 Q06124 1/20 0.31
HPRT1 P00492 1/20 0.31
ATIC P31939 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7037922 0.80 ALDH1A1 (0.36) ALDH1A1MEN1KMT2AKDM4ETDP1
SCHEMBL612167 0.77 ALDH1A1 (0.34) ALDH1A1MEN1KMT2AKDM4ETDP1
SCHEMBL7168417 0.77 ALDH1A1 (0.34) ALDH1A1MEN1KMT2AKDM4ETDP1
SCHEMBL9010837 0.77 ALDH1A1 (0.35) ALDH1A1MEN1KMT2AKDM4ETDP1
SCHEMBL28275704 0.73 ALDH1A1 (0.48) ALDH1A1KDM4ETDP1HPRT1HSD17B10
SCHEMBL28308645 0.70 FGFR1 (0.36) ALDH1A1DUSP3PTPN5PTPN11
SCHEMBL5616443 0.69 ALDH1A1 (0.44) ALDH1A1KDM4ETDP1HPRT1HSD17B10
SCHEMBL160199 0.68 GDA (0.37) ALDH1A1
SCHEMBL8903562 0.68 PIK3CD (0.35) ALDH1A1MEN1KMT2AKDM4E
SCHEMBL3306016 0.67 PNP (0.48) ALDH1A1MEN1KMT2AKDM4ETDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050148067-A1 Materials and methods for binding nucleic acids to surfaces LYLES MARK B (US) 2005-07-07 US claimed
US-6855817-B2 Materials and methods for binding nucleic acids to surfaces LYLES MARK B (US) 2005-02-15 US claimed
EP-1305328-A2 MATERIALS AND METHODS FOR BINDING NUCLEIC ACIDS TO SURFACES Lyles, Mark B. (US) 2003-05-02 EP claimed
US-20020103350-A1 Materials and methods for binding nucleic acids to surfaces LYLES MARK B (US) 2002-08-01 US claimed
WO-2002008237-A2 MATERIALS AND METHODS FOR BINDING NUCLEIC ACIDS TO SURFACES LYLES MARK B (US) 2002-01-31 WO claimed
US-7635491-B2 Method for administering selenium for treating patients suffering from systemic inflammatory response syndrome (SIRS), and composition for implementing the treatment Forceville, Xavier (FR) 2009-12-22 US disclosed
US-7247721-B2 Providing a mixture comprising nucleic acids and a charged material comprising any cationic purine; contacting the mixture and a surface to produce a bound material, wherein the bound material comprises nucleic acids covalenty bounded to the surface LYLES MARK B 2007-07-24 US disclosed
US-20050148067-A1 Materials and methods for binding nucleic acids to surfaces LYLES MARK B (US) 2005-07-07 US disclosed
US-6855817-B2 Materials and methods for binding nucleic acids to surfaces LYLES MARK B (US) 2005-02-15 US disclosed
EP-1305328-A2 MATERIALS AND METHODS FOR BINDING NUCLEIC ACIDS TO SURFACES Lyles, Mark B. (US) 2003-05-02 EP disclosed
US-20020103350-A1 Materials and methods for binding nucleic acids to surfaces LYLES MARK B (US) 2002-08-01 US disclosed
WO-2002008237-A2 MATERIALS AND METHODS FOR BINDING NUCLEIC ACIDS TO SURFACES LYLES MARK B (US) 2002-01-31 WO disclosed