SCHEMBL3757653

SCHEMBL3757653

Oc1ccc(C=C(Br)Br)cc1Br

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AMY1A P0DUB6 1/20 0.50
ALOX15 P16050 2/20 0.48
PRMT1 Q99873 1/20 0.47
EP300 Q09472 1/20 0.46
KMT2A Q03164 6/20 0.44
PKM P14618 1/20 0.44
F2R P25116 1/20 0.44
CISD1 Q9NZ45 2/20 0.44
PTP4A3 O75365 1/20 0.42
PTP4A1 Q93096 1/20 0.42
MEN1 O00255 5/20 0.41
HSP90AA1 P07900 1/20 0.41
ALDH1A1 P00352 2/20 0.40
PSMD14 O00487 1/20 0.40
CSNK2A1 P68400 2/20 0.40
SIRT1 Q96EB6 1/20 0.40
MKNK2 Q9HBH9 1/20 0.40
TRPA1 O75762 1/20 0.39
HSD17B3 P37058 1/20 0.39
CSNK2A2 P19784 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13082127 0.82 LCK (0.58) AMY1AALOX15KMT2APKMMEN1
SCHEMBL3759600 0.81 ALOX15 (0.46) AMY1AALOX15PRMT1EP300KMT2A
SCHEMBL3752323 0.77 TP53 (0.46) ALOX15KMT2APKMMEN1ALDH1A1
SCHEMBL3751900 0.77 TSHR (0.46) ALOX15KMT2AMEN1ALDH1A1SIRT1
SCHEMBL2885475 0.76 TRPA1 (0.52) AMY1AALOX15PRMT1EP300KMT2A
SCHEMBL190410 0.76 KDM4E (0.64) AMY1AALOX15PRMT1EP300KMT2A
SCHEMBL31380876 0.76 TRPA1 (0.52) AMY1AALOX15PRMT1EP300KMT2A
SCHEMBL29713168 0.76 KDM4E (0.64) AMY1AALOX15PRMT1EP300KMT2A
SCHEMBL9260391 0.75 PTGS2 (0.50) AMY1AALOX15PRMT1EP300KMT2A
SCHEMBL9260388 0.75 PTGS2 (0.50) AMY1AALOX15PRMT1EP300KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101888993-B Methoxyimino compounds and fungicide composition comprising same KYUNG NONG CORP 2013-08-21 CN disclosed
US-8410302-B2 Methoxyimino compounds and fungicide composition comprising same KYUNG NONG CORPORATION (KR) 2013-04-02 US disclosed
US-20100298593-A1 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME KYUNG NONG CORPORATION (KR) 2010-11-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100298593-A1 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME CYP51A1, MSMO1, MTMR1 AMY1A 1953/4885ALOX15 2235/4885PRMT1 892/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.