Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYCR1 | P32322 | 4/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21573669 | 0.82 | PYCR1 (0.36) | PYCR1CA1CA2ALDH1A1MAPK1 | |
| SCHEMBL307129 | 0.79 | PYCR1 (0.49) | PYCR1CA1CA2ALDH1A1MAPK1 | |
| SCHEMBL30169578 | 0.79 | PYCR1 (0.49) | PYCR1CA1CA2ALDH1A1MAPK1 | |
| SCHEMBL12164465 | 0.79 | PYCR1 (0.49) | PYCR1CA1CA2ALDH1A1MAPK1 | |
| SCHEMBL29676673 | 0.79 | PYCR1 (0.49) | PYCR1CA1CA2ALDH1A1MAPK1 | |
| SCHEMBL29418547 | 0.77 | PYCR1 (0.47) | PYCR1CA1CA2ALDH1A1MAPK1 | |
| SCHEMBL30352488 | 0.77 | PYCR1 (0.47) | PYCR1ALDH1A1MAPK1MAPTKDM5A | |
| SCHEMBL607749 | 0.77 | PYCR1 (0.47) | PYCR1CA1CA2ALDH1A1MAPK1 | |
| SCHEMBL8587112 | 0.77 | PYCR1 (0.47) | PYCR1CA1CA2ALDH1A1MAPK1 | |
| SCHEMBL12053 | 0.77 | PYCR1 (0.47) | PYCR1CA1CA2ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022240830-A1 | C-LINKED INHIBITORS OF ENL/AF9 YEATS | BRIDGE MEDICINES (US) | 2022-11-17 | — | — | WO | disclosed |
| EP-1810972-B1 | NITROGENOUS HETEROCYCLIC COMPOUND AND PHARMACEUTICAL USE THEREOF | ONO PHARMACEUTICAL CO (JP) | 2012-01-25 | — | — | EP | disclosed |