Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYCR1 | P32322 | 4/20 | 0.47 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | PON1 | P27169 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29418547 | 1.00 | PYCR1 (0.47) | PYCR1KDM5AKDM4CKDM5BALDH1A1 | |
| SCHEMBL30831861 | 0.82 | PYCR1 (0.36) | PYCR1ALDH1A1MAPK1MAPTPON1 | |
| SCHEMBL2807248 | 0.82 | PYCR1 (0.36) | PYCR1ALDH1A1MAPK1MAPTPON1 | |
| SCHEMBL29676673 | 0.79 | PYCR1 (0.49) | PYCR1KDM5AKDM4CKDM5BALDH1A1 | |
| SCHEMBL30169578 | 0.79 | PYCR1 (0.49) | PYCR1KDM5AKDM4CKDM5BALDH1A1 | |
| SCHEMBL12164465 | 0.79 | PYCR1 (0.49) | PYCR1KDM5AKDM4CKDM5BALDH1A1 | |
| SCHEMBL307129 | 0.79 | PYCR1 (0.49) | PYCR1KDM5AKDM4CKDM5BALDH1A1 | |
| SCHEMBL1561687 | 0.78 | CYP2A6 (0.35) | PYCR1ALDH1A1MAPK1CYP1A2CYP2C9 | |
| SCHEMBL375783 | 0.77 | PYCR1 (0.47) | PYCR1KDM5AKDM4CKDM5BALDH1A1 | |
| SCHEMBL8587112 | 0.77 | PYCR1 (0.47) | PYCR1KDM5AKDM4CKDM5BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118307540-A | Synthesis method of avibactam sodium | 浙江尖峰药业有限公司 | 2024-07-09 | — | — | CN | claimed |
| US-12565500-B2 | Substituted pyrrolo[1,2-b]pyridazines and pyrrolo[2,1-f][1,2,4]triazines as Btk inhibitors | BIOGEN MA INC. (US) | 2026-03-03 | — | — | US | disclosed |
| EP-4051679-B1 | CONDENSED PYRIDAZINE OR PYRIMIDINE AS BTK INHIBITORS | BIOGEN MA INC (US) | 2025-08-06 | — | — | EP | disclosed |
| US-20250034150-A1 | BTK INHIBITORS | BIOGEN MA INC. | 2025-01-30 | — | — | US | disclosed |
| US-20240327380-A1 | BTK INHIBITORS | BIOGEN MA INC. (US) | 2024-10-03 | — | — | US | disclosed |
| EP-4429770-A1 | BTK INHIBITORS | Biogen MA Inc. (US) | 2024-09-18 | — | — | EP | disclosed |
| CN-118307540-A | Synthesis method of avibactam sodium | 浙江尖峰药业有限公司 | 2024-07-09 | — | — | CN | disclosed |
| CN-110536885-B | Process for producing difluoromethylene compound | 佐藤制药株式会社 | 2024-03-08 | — | — | CN | disclosed |
| CN-116917279-A | BTK inhibitors | 渤健马萨诸塞州股份有限公司 | 2023-10-20 | — | — | CN | disclosed |
| EP-4192587-A1 | BTK INHIBITORS | Biogen MA Inc. (US) | 2023-06-14 | — | — | EP | disclosed |
| CN-100351263-C | Pyrazole derivative, medicinal composition containing the same, medicinal use thereof, and intermediate for production thereof | KISSEI PHARMACEUTICAL COMPANY (JP) | 2007-11-28 | — | — | CN | disclosed |
| US-20060166899-A1 | Pyrazole derivative, medicinal composition containing the same, medicinal use thereof, and intermediate for production thereof | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2006-07-27 | — | — | US | disclosed |
| US-20050272669-A1 | Pyrazole derivatives, medicinal composition containing the same, medicinal use thereof, and intermediate for production thereof | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2005-12-08 | — | — | US | disclosed |
| CN-1688597-A | Pyrazole derivatives, medicinal composition containing the same, medicinal use thereof, and intermediate for production thereof | KISSEI PHARMACEUTICAL COMPANY (JP) | 2005-10-26 | — | — | CN | disclosed |
| CN-1688596-A | Pyrazole derivative, medicinal composition containing the same, medicinal use thereof, and intermediate for production thereof | KISSEI PHARMACEUTICAL COMPANY (JP) | 2005-10-26 | — | — | CN | disclosed |
| EP-1548024-A1 | PYRAZOLE DERIVATIVES, MEDICINAL COMPOSITION CONTAINING THE SAME, MEDICINAL USE THEREOF, AND INTERMEDIATE FOR PRODUCTION THEREOF | Kissei Pharmaceutical Co., Ltd. (JP) | 2005-06-29 | — | — | EP | disclosed |
| EP-1544208-A1 | PYRAZOLE DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, MEDICINAL USE THEREOF, AND INTERMEDIATE FOR PRODUCTION THEREOF | Kissei Pharmaceutical Co., Ltd. (JP) | 2005-06-22 | — | — | EP | disclosed |
| US-4990716-A | Preparation of diphenylmethanes | THE DOW CHEMICAL COMPANY (US) | 1991-02-05 | — | — | US | disclosed |
| US-4117019-A | MANUFACTURE OF O-BENZYLTOLUENES | BASF AKTIENGESELLSCHAFT (DE) | 1978-09-26 | — | — | US | disclosed |
| US-3978144-A | MANUFACTURE OF O-BENZYLTOLUENES | BASF AKTIENGESELLSCHAFT (DT) | 1976-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060166899-A1 | Pyrazole derivative, medicinal composition containing the same, medicinal use thereof, and intermediate for production thereof | SLC5A1, SLC5A2, SULT2A1 | PYCR1 491/4885KDM5A 1727/4885KDM4C 2482/4885 |
| US-20240327380-A1 | BTK INHIBITORS | BTK, SYK, LYN | PYCR1 4152/4885KDM5A 1542/4885KDM4C 2129/4885 |
| US-20050272669-A1 | Pyrazole derivatives, medicinal composition containing the same, medicinal use thereof, and intermediate for production thereof | UGGT1, GCKR, SLC5A1 | PYCR1 780/4885KDM5A 2498/4885KDM4C 1209/4885 |
| US-20250034150-A1 | BTK INHIBITORS | BTK, SYK, LYN | PYCR1 4526/4885KDM5A 1733/4885KDM4C 2564/4885 |
| US-12565500-B2 | Substituted pyrrolo[1,2-b]pyridazines and pyrrolo[2,1-f][1,2,4]triazines as Btk inhibitors | BTK, SYK, OXSR1 | PYCR1 2236/4885KDM5A 1528/4885KDM4C 3204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.