Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.60 |
| ▸ | RAB9A | P51151 | 7/20 | 0.60 |
| ▸ | ATG4B | Q9Y4P1 | 6/20 | 0.60 |
| ▸ | NPC1 | O15118 | 6/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | CDK2 | P24941 | 1/20 | 0.60 |
| ▸ | GSK3A | P49840 | 1/20 | 0.60 |
| ▸ | GSK3B | P49841 | 1/20 | 0.60 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.60 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.60 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | NSD2 | O96028 | 1/20 | 0.52 |
| ▸ | ALPL | P05186 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18529268 | 0.84 | ATG4B (0.67) | MEN1KMT2ARAB9AATG4BNPC1 | |
| SCHEMBL881350 | 0.84 | MEN1 (0.63) | MEN1KMT2ARAB9AATG4BNPC1 | |
| Hydrochloric Acid SCHEMBL1392257 | 0.83 | MEN1 (0.61) | MEN1KMT2ARAB9AATG4BNPC1 | |
| Hydrochloric Acid SCHEMBL1392255 | 0.83 | MEN1 (0.61) | MEN1KMT2ARAB9AATG4BNPC1 | |
| SCHEMBL27550543 | 0.80 | CDK2 (0.63) | MEN1KMT2AMAPTHTTCDK2 | |
| SCHEMBL5835803 | 0.80 | CDK2 (0.63) | MEN1KMT2AMAPTHTTCDK2 | |
| SCHEMBL13694246 | 0.77 | MEN1 (0.77) | MEN1KMT2ARAB9AATG4BNPC1 | |
| SCHEMBL376024 | 0.77 | MEN1 (0.54) | MEN1KMT2ARAB9AATG4BNPC1 | |
| SCHEMBL18529266 | 0.75 | RAB9A (1.00) | MEN1KMT2ARAB9AATG4BNPC1 | |
| SCHEMBL1394887 | 0.75 | ATG4B (1.00) | ATG4BCDK2GSK3AGSK3BDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2632460-A2 | COMPOSITIONS AND METHODS FOR TREATING TUBERCULOSIS | University Of Virginia Patent Foundation (US) | 2013-09-04 | — | — | EP | disclosed |
| WO-2012040170-A2 | COMPOSITIONS AND METHODS FOR TREATING TUBERCULOSIS | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2012-03-29 | — | — | WO | disclosed |
| EP-2408770-A2 | BROAD SPECTRUM BENZOTHIOPHENE-NITROTHIAZOLIDE AND OTHER ANTIMICROBIALS | University Of Virginia Patent Foundation (US) | 2012-01-25 | — | — | EP | disclosed |
| WO-2010107736-A2 | BROAD SPECTRUM BENZOTHIOPHENE-NITROTHIAZOLIDE AND OTHER ANTIMICROBIALS | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2010-09-23 | — | — | WO | disclosed |