SCHEMBL37581

SCHEMBL37581

N#CCc1cccc(Cl)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 2/20 0.54
ENPP2 Q13822 1/20 0.53
KDM4E B2RXH2 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
NPC1 O15118 1/20 0.51
LMNA P02545 1/20 0.51
MAPT P10636 1/20 0.51
HTT P42858 1/20 0.51
TAAR1 Q96RJ0 3/20 0.50
MMP3 P08254 1/20 0.50
KMT2A Q03164 1/20 0.49
ATM Q13315 1/20 0.49
CYP3A4 P08684 2/20 0.48
IDO1 P14902 2/20 0.48
AGXT P21549 2/20 0.48
HTR3E A5X5Y0 2/20 0.46
HTR3B O95264 2/20 0.46
HTR3A P46098 2/20 0.46
HTR3D Q70Z44 2/20 0.46
HTR3C Q8WXA8 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29700969 1.00 PNMT (0.54) PNMTENPP2KDM4ETDP1NPC1
SCHEMBL8993095 0.87 NPC1 (0.52) PNMTENPP2KDM4ETDP1NPC1
SCHEMBL10547199 0.84 AR (0.48) ENPP2NPC1LMNAMAPTHTT
SCHEMBL237972 0.84 ENPP2 (0.63) ENPP2KDM4ETDP1NPC1LMNA
Benzene SCHEMBL5438521 0.81 ENPP2 (0.61) ENPP2KDM4ETDP1MMP3KMT2A
SCHEMBL2986537 0.79 KMT2A (0.73) PNMTTAAR1KMT2AATMCYP3A4
SCHEMBL17873550 0.79 MMP3 (0.70) ENPP2KDM4ETDP1NPC1LMNA
SCHEMBL10548363 0.79 ENPP2 (0.46) ENPP2KDM4ETDP1NPC1LMNA
SCHEMBL2952761 0.78 PNMT (0.54) PNMTTAAR1CYP3A4IDO1AGXT
SCHEMBL1759063 0.78 TAAR1 (0.55) PNMTTAAR1CYP3A4IDO1AGXT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 582 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109232643-B Preparation method of phosphamide cattle feed additive 沈阳富士大通科技有限公司 2020-08-21 CN claimed
CN-109613155-A A kind of detection method of armaticity nitrogenous disinfection byproducts 同济大学 2019-04-12 CN claimed
CN-109232643-A A kind of preparation method of phosphoramide types ox feed additive 河南湾流生物科技有限公司 2019-01-18 CN claimed
US-7923110-B2 Metal nanoparticle having a self-assembled monolayer on its surface, and formation of conductive pattern using the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2011-04-12 US claimed
US-20080020317-A1 Novel metal nanoparticle and formation of conductive pattern using the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2008-01-24 US claimed
US-20080003363-A1 Novel metal nanoparticle and method for formation of conductive pattern using the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2008-01-03 US claimed
US-4046814-A Preparation of diketones WRIGHT STATE UNIVERSITY (US) 1977-09-06 US claimed
JP-5034732-A None JP disclosed
EP-4709708-A1 NOVEL CARBOXAMIDE DERIVATIVES ANGELINI PHARMA S.P.A. (IT) 2026-03-18 EP disclosed
US-20250320217-A1 SUBSTITUTED IMIDAZO[1,2-B]PYRIDAZINES AS PROTEIN KINASE INHIBITORS SUMITOMO PHARMA AMERICA INC (US) 2025-10-16 US disclosed
EP-4623032-A2 YELLOW METHINE DYES AND THEIR USE FOR DYEING PLASTICS LANXESS Deutschland GmbH (DE) 2025-10-01 EP disclosed
US-20250129085-A1 SUBSTITUTED IMIDAZO[1,2-B]PYRIDAZINES AS PROTEIN KINASE INHIBITORS SUMITOMO PHARMA AMERICA INC (US) 2025-04-24 US disclosed
WO-2025031396-A1 SUBSTITUTED BENZOCYCLOBUTENE COMPOUND AND USES THEREOF IN THE FIELD OF MEDICINE 杭州安道药业有限公司 2025-02-13 WO disclosed
US-4046814-A Preparation of diketones WRIGHT STATE UNIVERSITY (US) 1977-09-06 US disclosed
US-4017500-A FUNGICIDES, BACTERICIDES SCHERING CORPORATION (US) 1977-04-12 US disclosed
US-4012224-A Herbicidal use of β-aminoatroponitriles ELI LILLY AND COMPANY (US) 1977-03-15 US disclosed
US-3984559-A Compositions comprising tetramic acid analogs of pulvinic acid and methods of combating arthritis SMITHKLINE CORPORATION (US) 1976-10-05 US disclosed
US-3947580-A Anti-arthritic compositions comprising N-heterocyclic pulvinic acid amides and methods of producing anti-arthritic activity SMITHKLINE CORPORATION (US) 1976-03-30 US disclosed
US-3944571-A ANTIARTHRITIC SMITHKLINE CORPORATION (US) 1976-03-16 US disclosed
US-3931207-A ANTIARTHRITIC SMITHKLINE CORPORATION (US) 1976-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250129085-A1 SUBSTITUTED IMIDAZO[1,2-B]PYRIDAZINES AS PROTEIN KINASE INHIBITORS PIM1, PIM2, PIM3 PNMT 1378/4885ENPP2 1417/4885KDM4E 1020/4885
US-20250320217-A1 SUBSTITUTED IMIDAZO[1,2-B]PYRIDAZINES AS PROTEIN KINASE INHIBITORS PIM1, PIM2, PIM3 PNMT 1378/4885ENPP2 1417/4885KDM4E 1020/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.