Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15196404 | 0.88 | GPR119 (0.61) | GPR119CYP2C9 | |
| SCHEMBL4479956 | 0.83 | GPR119 (0.57) | GPR119CYP2C9 | |
| SCHEMBL4495357 | 0.83 | GPR119 (0.55) | GPR119CYP2C9 | |
| SCHEMBL12170572 | 0.81 | EIF4E (0.46) | GPR119CYP2C9 | |
| SCHEMBL4499334 | 0.80 | GPR119 (0.46) | GPR119CYP2C9 | |
| SCHEMBL4492691 | 0.80 | GPR119 (0.46) | GPR119CYP2C9 | |
| SCHEMBL4482969 | 0.79 | GPR119 (0.39) | GPR119CYP2C9 | |
| SCHEMBL11315388 | 0.78 | GPR119 (0.86) | GPR119CYP2C9 | |
| SCHEMBL4493052 | 0.76 | GPR119 (1.00) | GPR119CYP2C9 | |
| SCHEMBL4491731 | 0.76 | GPR119 (0.77) | GPR119CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8222261-B2 | Chemical compounds | GlaxoSmithKline, LLC (US) | 2012-07-17 | — | — | US | disclosed |
| US-20120095028-A1 | 3-OXA-7-AZABICYCLO[3.3.1]NONANES | PFIZER INC. | 2012-04-19 | — | — | US | disclosed |
| EP-2408780-A2 | 3-OXA-7-AZABICYCLOÝ3.3.1¨NONANES | Pfizer Inc. (US) | 2012-01-25 | — | — | EP | disclosed |
| WO-2010106457-A2 | 3-OXA-7-AZABICYCLO[3.3.1]NONANES | PFIZER INC. (US) | 2010-09-23 | — | — | WO | disclosed |
| US-20090318477-A1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE LLC | 2009-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120095028-A1 | 3-OXA-7-AZABICYCLO[3.3.1]NONANES | GPR119, GPR27, GPBAR1 | GPR119 1/4885CYP2C9 835/4885 |
| US-20090318477-A1 | CHEMICAL COMPOUNDS | GPR119, GOT2, SLC5A2 | GPR119 1/4885CYP2C9 971/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.