Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | APAF1 | O14727 | 2/20 | 0.43 |
| ▸ | TDP2 | O95551 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | TERT | O14746 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PTPRC | P08575 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL14931822 | 0.84 | MEN1 (0.50) | CA2CA4CA5AMEN1KMT2A | |
| Phosphoric Acid SCHEMBL27648570 | 0.84 | MEN1 (0.50) | CA2CA4CA5AMEN1KMT2A | |
| Pyrophosphoric Acid SCHEMBL4104677 | 0.74 | BLM (0.56) | CA2CA4CA5AMEN1KMT2A | |
| Biphenyl SCHEMBL27796608 | 0.74 | PTPN5 (0.56) | CA2CA4CA5ANPC1RAB9A | |
| Iodide SCHEMBL28650690 | 0.73 | — | — | |
| Iodide SCHEMBL3851713 | 0.73 | — | — | |
| Iodide SCHEMBL1109613 | 0.73 | CA2 (0.42) | CA2MAPK1KDM4ETHRBBLM | |
| Iodide SCHEMBL1425585 | 0.73 | CA2 (0.42) | CA2MAPK1KDM4ETHRBBLM | |
| Iodide SCHEMBL219547 | 0.73 | MEN1 (0.57) | MEN1KMT2AAPAF1TDP2MAPK1 | |
| SCHEMBL31460269 | 0.72 | CA2 (0.46) | CA2CA4CA5AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8084522-B2 | Thermally stable cationic photocurable compositions | BASF SE (DE) | 2011-12-27 | — | — | US | disclosed |
| US-20100304284-A1 | THERMALLY STABLE CATIONIC PHOTOCURABLE COMPOSITIONS | IGM GROUP B.V. (NL) | 2010-12-02 | — | — | US | disclosed |