Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | APAF1 | O14727 | 2/20 | 0.50 |
| ▸ | TDP2 | O95551 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | S100A4 | P26447 | 2/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | TERT | O14746 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.50 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL14931822 | 1.00 | MEN1 (0.50) | MEN1KMT2AAPAF1TDP2CA2 | |
| Phosphoric Acid SCHEMBL242260 | 0.86 | ALDH1A1 (0.50) | CA2MAPK1CA4CA5AALDH1A1 | |
| Iodide SCHEMBL3760503 | 0.84 | CA2 (0.43) | MEN1KMT2AAPAF1TDP2CA2 | |
| Anthraquinone SCHEMBL27831869 | 0.84 | MEN1 (0.71) | MEN1KMT2AAPAF1TDP2MAPK1 | |
| Pyrophosphoric Acid SCHEMBL4104677 | 0.82 | BLM (0.56) | MEN1KMT2AAPAF1TDP2CA2 | |
| Phosphoric Acid SCHEMBL29542627 | 0.82 | ALDH1A1 (0.52) | KMT2ACA2MAPK1CA4CA5A | |
| Phosphoric Acid SCHEMBL1281473 | 0.82 | ALDH1A1 (0.52) | KMT2ACA2MAPK1CA4CA5A | |
| Phosphoric Acid SCHEMBL31187365 | 0.82 | ALDH1A1 (0.52) | MEN1KMT2AAPAF1TDP2CA2 | |
| Phosphoric Acid SCHEMBL4104685 | 0.79 | CA2 (0.50) | MEN1KMT2ACA2CA4CA5A | |
| Naphthalene SCHEMBL3796240 | 0.79 | CYP2A6 (0.57) | CA2CA4CA5ACES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103476764-A | Process for producing episulfide compound | ASAHI KASEI CHEMICALS CORP (JP) | 2013-12-25 | — | — | CN | disclosed |
| CN-101278002-B | Method for producing crystal nucleus agent composition and crystalline polymer composition | ADEKA CORP | 2012-04-04 | — | — | CN | disclosed |
| CN-1813021-A | Method for producing cycloolefin resin film or sheet | JSR CORP (JP) | 2006-08-02 | — | — | CN | disclosed |