SCHEMBL3761265

SCHEMBL3761265

COc1ccc(C2([C]=O)N=C(c3ccccc3)C(c3ccccc3)=N2)c(OC)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.40
MEN1 O00255 5/20 0.40
KMT2A Q03164 5/20 0.40
SMN1; SMN2 Q16637 4/20 0.40
ALDH1A1 P00352 4/20 0.40
CYP1A1 P04798 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2E1 P05181 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2C8 P10632 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2A6 P11509 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP4B1 P13584 1/20 0.40
CYP2B6 P20813 1/20 0.40
CYP3A5 P20815 1/20 0.40
CYP2A7 P20853 1/20 0.40
CYP3A7 P24462 1/20 0.40
CYP2F1 P24903 1/20 0.40
CYP2C18 P33260 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL491149 0.82 CYP1A1 (0.45) KDM4EMEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL3753586 0.79 BACE1 (0.41) KDM4EKMT2AALDH1A1MAPTL3MBTL1
SCHEMBL8668382 0.70 CYP3A4 (0.44) KDM4EMEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL11269310 0.70 KDM4E (0.40) KDM4EMEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL3757997 0.68 CRHBP (0.36) ALDH1A1CYP2A6TSHR
SCHEMBL5321200 0.67 CYP3A4 (0.65) KDM4EMEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL1132026 0.66 CYP1A1 (0.58) KDM4EMEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL490715 0.65 AKR1C3 (0.46) KDM4EMEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL5632975 0.65 CYP1A1 (0.79) KDM4EMEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL152089 0.64 CA12 (0.41) KDM4EKMT2ASMN1; SMN2ALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2629149-A2 Colored curable composition, color filter and manufacturing method thereof Fujifilm Corporation (JP) 2013-08-21 EP disclosed
US-7842440-B2 Colored curable composition, color filter and manufacturing method thereof FUJIFILM CORPORATION (JP) 2010-11-30 US disclosed
US-20090047585-A1 Colored curable composition, color filter and manufacturing method thereof FUJIFILM CORPORATION (JP) 2009-02-19 US disclosed
EP-1780598-A1 COLORED CURABLE COMPOSITIONS, COLOR FILTERS AND PROCESS FOR PRODUCTION THEREOF FUJIFILM Corporation (JP) 2007-05-02 EP disclosed