Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11268438 | 0.85 | ALDH1A1 (0.43) | KDM4ENPC1RAB9AALDH1A1HPGD | |
| SCHEMBL491149 | 0.84 | CYP1A1 (0.45) | KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL11278246 | 0.82 | ALDH1A1 (0.45) | NPC1RAB9ASMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL490794 | 0.82 | RELA (0.40) | KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL29660677 | 0.81 | DYRK1A (0.43) | KDM4ENPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL82380 | 0.81 | DYRK1A (0.43) | KDM4ENPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL80380 | 0.80 | CHRM1 (0.41) | NPC1RAB9ASMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL82274 | 0.76 | TAAR1 (0.40) | KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL29362744 | 0.76 | TAAR1 (0.40) | KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8667011 | 0.75 | ABL1 (0.46) | KDM4ENPC1RAB9AALDH1A1AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4332884-A | USING A DIOXIME CHELATING AGENT | RICOH CO., LTD. (JP) | 1982-06-01 | — | — | US | disclosed |
| US-4315068-A | CONTAINING A COBALT-AMMINE COMPLEX AND A DIOXIME OR A BISIMIDAZOLIN-3-ONE CHELATING AGENT; STABILITY; COLOR DILMS | RICOH CO., LTD. (JP) | 1982-02-09 | — | — | US | disclosed |
| US-4306014-A | AMMONIA OR AMINES SUPPRESS THE COLOR-FORMING REACTION SYSTEM | RICOH CO., LTD. (JP) | 1981-12-15 | — | — | US | disclosed |