SCHEMBL3753586

SCHEMBL3753586

COc1ccc(C2([C]=O)N=C(c3ccccc3)C(c3ccccc3)=N2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 3/20 0.41
BACE2 Q9Y5Z0 1/20 0.41
GFER P55789 1/20 0.41
ALDH1A1 P00352 3/20 0.41
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
KDM4E B2RXH2 1/20 0.41
LMNA P02545 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
EDNRA P25101 1/20 0.40
OPRM1 P35372 1/20 0.40
OPRL1 P41146 1/20 0.40
MAPT P10636 3/20 0.39
CA4 P22748 1/20 0.38
LTA4H P09960 1/20 0.38
MAPK1 P28482 1/20 0.38
KMT2A Q03164 1/20 0.38
RPA1 P27694 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3761265 0.79 KDM4E (0.40) BACE1ALDH1A1NPC1RAB9AKDM4E
SCHEMBL150156 0.79 ALDH1A1 (0.46) BACE1BACE2GFERALDH1A1NPC1
SCHEMBL3761239 0.79 PTGS2 (0.43) ALDH1A1NPC1RAB9AKDM4EMAPT
SCHEMBL8664760 0.78 NPC1 (0.49) BACE1BACE2GFERALDH1A1NPC1
SCHEMBL11595707 0.72 KDM4E (0.46) BACE1BACE2ALDH1A1NPC1RAB9A
SCHEMBL491148 0.70 SYK (0.42) BACE1ALDH1A1NPC1RAB9AKDM4E
SCHEMBL11798458 0.69 NPC1 (0.58) BACE1GFERALDH1A1NPC1RAB9A
SCHEMBL8667011 0.67 ABL1 (0.46) BACE1ALDH1A1NPC1RAB9AKDM4E
SCHEMBL11268438 0.66 ALDH1A1 (0.43) BACE1GFERALDH1A1NPC1RAB9A
SCHEMBL9152375 0.66 CA4 (0.68) BACE1ALDH1A1NPC1RAB9AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2629149-A2 Colored curable composition, color filter and manufacturing method thereof Fujifilm Corporation (JP) 2013-08-21 EP disclosed
US-7842440-B2 Colored curable composition, color filter and manufacturing method thereof FUJIFILM CORPORATION (JP) 2010-11-30 US disclosed
US-20090047585-A1 Colored curable composition, color filter and manufacturing method thereof FUJIFILM CORPORATION (JP) 2009-02-19 US disclosed
EP-1780598-A1 COLORED CURABLE COMPOSITIONS, COLOR FILTERS AND PROCESS FOR PRODUCTION THEREOF FUJIFILM Corporation (JP) 2007-05-02 EP disclosed