SCHEMBL376139

SCHEMBL376139

Nc1nc2c(ncn2[C@@H]2O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]2O)c(=O)[nH]1

nearest known ligand 0.81

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 1/20 0.81
NT5E P21589 1/20 0.76
KRAS P01116 2/20 0.76
FUT5 Q11128 1/20 0.75
P2RX3 P56373 2/20 0.71
P2RY6 Q15077 2/20 0.71
P2RY2 P41231 1/20 0.71
P2RY4 P51582 1/20 0.71
P2RY1 P47900 4/20 0.68
ENPP1 P22413 2/20 0.68
P2RX1 P51575 1/20 0.68
P2RY11 Q96G91 1/20 0.68
P2RX4 Q99571 1/20 0.68
P2RY12 Q9H244 1/20 0.66
IMPDH2 P12268 5/20 0.65
IMPDH1 P20839 1/20 0.65
DCPS Q96C86 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Gtp SCHEMBL18271799 1.00 TGM2 (0.81) TGM2NT5EKRASFUT5P2RX3
Gtp SCHEMBL3333959 1.00 TGM2 (0.81) TGM2NT5EKRASFUT5P2RX3
SCHEMBL376140 1.00 TGM2 (0.81) TGM2NT5EKRASFUT5P2RX3
Gtp SCHEMBL18784960 1.00 TGM2 (0.81) TGM2NT5EKRASFUT5P2RX3
SCHEMBL1304258 1.00 TGM2 (0.81) TGM2NT5EKRASFUT5P2RX3
SCHEMBL19691775 1.00 TGM2 (0.81) TGM2NT5EKRASFUT5P2RX3
SCHEMBL2593095 1.00 TGM2 (0.81) TGM2NT5EKRASFUT5P2RX3
Gtp SCHEMBL5809658 1.00 TGM2 (0.81) TGM2NT5EKRASFUT5P2RX3
Gtp SCHEMBL17367368 1.00 TGM2 (0.81) TGM2NT5EKRASFUT5P2RX3
Gtp SCHEMBL96708 1.00 TGM2 (0.81) TGM2NT5EKRASFUT5P2RX3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 264 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024155027-A1 ATTENUATED SALMONELLA GALLINARUM EXPRESSING FLIC OR FLIC-HIL2 AND USE THEREOF 주식회사 오디세우스바이오 2024-07-25 WO claimed
US-20240240140-A1 ATTENUATED SALMONELLA GALLINARUM EXPRESSING FLIC OR FLIC-HIL2 AND USES THEREOF Odysseus Bio Co., Ltd. (KR) 2024-07-18 US claimed
US-20240218318-A1 ATTENUATED SALMONELLA GALLINARUM STRAIN AND USE THEREOF Odysseus Bio Co., Ltd. (KR) 2024-07-04 US claimed
US-20240108664-A1 TUMOR-TARGETING SALMONELLA GALLINARUM STRAIN AND USE THEREOF INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY (KR) 2024-04-04 US claimed
EP-4332228-A1 ATTENUATED SALMONELLA GALLINARUM STRAIN AND USE THEREOF Industry Foundation of Chonnam National University (KR) 2024-03-06 EP claimed
CN-117480255-A Attenuated salmonella gallinarum strain and use thereof 全南大学校产学协力团 2024-01-30 CN claimed
CN-114324540-B Guanosine tetraphosphoric acid electrochemical nano-enzyme sensor and preparation method thereof 天津商业大学 2023-12-26 CN claimed
CN-115943211-A Tumor-targeted salmonella gallinarum strain and application thereof 全南大学校产学协力团 2023-04-07 CN claimed
CN-115844804-A Composition for improving exogenous aging and preparation method and application thereof 湖北省吉美化妆品有限公司 2023-03-28 CN claimed
CN-115813803-A Composition capable of improving skin anti-wrinkle, moisturizing and whitening effects on cell layer 广州时光之城科技有限公司 2023-03-21 CN claimed
EP-1451211-A2 COMPOSITIONS AND METHODS FOR MODULATING GUANYLYL CYCLASE SIGNALING RECEPTOR (GC-C) ACTIVITY AND FOR TREATING MENIERE'S DISEASE University of Copenhagen (DK) 2004-09-01 EP claimed
US-20040152868-A1 Compositions and methods for modulating guanylyl cyclase signaling receptor (gc-c) activity and for treating meniere's disease UNIVERSITY OF COPENHAGEN (DK) 2004-08-05 US claimed
US-6562801-B1 PpGpp and pppGpp as immunomodulatory agents BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2003-05-13 US claimed
US-20030039657-A1 Inducible vaccines BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2003-02-27 US claimed
WO-2002079235-A2 COMPOSITIONS AND METHODS FOR MODULATING GUANYLYL CYCLASE SIGNALING RECEPTOR (GC-C) ACTIVITY AND FOR TREATING MENIERE'S DISEASE UNIVERSITY OF COPENHAGEN (US) 2002-10-10 WO claimed
WO-2000062817-A2 INDUCIBLE VACCINES BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2000-10-26 WO claimed
WO-2000062803-A2 ppGpp AND pppGpp AS IMMUNOMODULATORY AGENTS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2000-10-26 WO claimed
EP-1005327-A1 TARGETED LIPOSOMAL CONSTRUCTS FOR DIAGNOSTIC AND THERAPEUTIC USES SDG, INC. (US) 2000-06-07 EP claimed
US-6063400-A CARRIER; DIAGNOSTIC OR THERAPEUTIC AGENT AND SEQUESTERING AGENT SDG, INC. (US) 2000-05-16 US claimed
WO-1999001110-A1 TARGETED LIPOSOMAL CONSTRUCTS FOR DIAGNOSTIC AND THERAPEUTIC USES SDG, INC. (US) 1999-01-14 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040152868-A1 Compositions and methods for modulating guanylyl cyclase signaling receptor (gc-c) activity and for treating meniere's disease PDE7A, PDE6C, PDE9A TGM2 1239/4885NT5E 397/4885KRAS 2610/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.