Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | F2 | P00734 | 3/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | EDNRA | P25101 | 4/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6046339 | 0.81 | CA2 (0.61) | CA2F2PRSS1PRSS2PRSS3 | |
| SCHEMBL1268593 | 0.81 | CA2 (0.54) | CA2F2PRSS1PRSS2PRSS3 | |
| SCHEMBL1105200 | 0.81 | CA2 (0.65) | CA2F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7558142 | 0.78 | CA2 (0.61) | CA2F2PRSS1PRSS2PRSS3 | |
| SCHEMBL28337330 | 0.76 | CA2 (0.55) | CA2F2PRSS1PRSS2PRSS3 | |
| SCHEMBL28046229 | 0.76 | CA2 (0.59) | CA2F2PRSS1PRSS2PRSS3 | |
| SCHEMBL28751226 | 0.76 | F2 (0.56) | CA2F2PRSS1PRSS2PRSS3 | |
| SCHEMBL214991 | 0.75 | CA2 (0.57) | CA2F2PRSS1PRSS2PRSS3 | |
| SCHEMBL133520 | 0.74 | CA2 (0.69) | CA2F2PRSS1PRSS2PRSS3 | |
| SCHEMBL29941705 | 0.74 | CA2 (0.69) | CA2F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8754252-B2 | Asymmetric cyclization processes using unsaturated nitro compounds | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2014-06-17 | — | — | US | disclosed |
| US-20130096338-A1 | ASYMMETRIC CYCLIZATION PROCESSES USING UNSATURATED NITRO COMPOUNDS | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2013-04-18 | — | — | US | disclosed |
| US-20100298576-A1 | ASYMMETRIC CYCLIZATION PROCESSES USING UNSATURATED NITRO COMPOUNDS | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2010-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130096338-A1 | ASYMMETRIC CYCLIZATION PROCESSES USING UNSATURATED NITRO COMPOUNDS | NQO1, COASY, NOS2 | CA2 3725/4885F2 1363/4885PRSS1 4002/4885 |
| US-20100298576-A1 | ASYMMETRIC CYCLIZATION PROCESSES USING UNSATURATED NITRO COMPOUNDS | NQO1, COASY, NOS2 | CA2 3725/4885F2 1363/4885PRSS1 4002/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.