Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.73 |
| ▸ | DRD4 | P21917 | 5/20 | 0.73 |
| ▸ | DRD3 | P35462 | 4/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5279270 | 0.88 | DRD2 (0.72) | DRD2DRD4DRD3L3MBTL1TDP1 | |
| SCHEMBL386935 | 0.87 | L3MBTL1 (0.65) | DRD2DRD4DRD3L3MBTL1TDP1 | |
| SCHEMBL8067303 | 0.87 | L3MBTL1 (0.64) | DRD2DRD4DRD3L3MBTL1TDP1 | |
| SCHEMBL12301162 | 0.87 | TDP1 (0.69) | DRD2DRD4DRD3L3MBTL1TDP1 | |
| SCHEMBL1592876 | 0.85 | TDP1 (0.60) | DRD2DRD4DRD3L3MBTL1TDP1 | |
| SCHEMBL5289799 | 0.85 | L3MBTL1 (0.59) | DRD2DRD4DRD3L3MBTL1TDP1 | |
| SCHEMBL3762419 | 0.85 | HTR1B (0.57) | DRD2DRD4DRD3L3MBTL1TDP1 | |
| SCHEMBL3757321 | 0.85 | DRD2 (0.59) | DRD2DRD4DRD3L3MBTL1TDP1 | |
| SCHEMBL10707303 | 0.85 | TDP1 (0.63) | DRD2DRD4DRD3L3MBTL1TDP1 | |
| P-Xylene SCHEMBL817546 | 0.85 | DRD2 (0.55) | DRD2DRD4DRD3L3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4010978-A | — | — | None | — | — | JP | disclosed |
| CN-102712202-B | Thermosensitive type lithographic plate and printing process thereof | MITSUBISHI PAPER MILLS LTD. (JP) | 2015-10-21 | — | — | CN | disclosed |
| US-9056862-B2 | Thioxothiazolidine derivative having Ras function inhibitory effect | NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) | 2015-06-16 | — | — | US | disclosed |
| US-9056862-B2 | Thioxothiazolidine derivative having Ras function inhibitory effect | NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) | 2015-06-16 | — | — | US | disclosed |
| US-8978553-B2 | Heat-sensitive lithographic printing plates | MITSUBISHI PAPER MILLS LIMITED (JP) | 2015-03-17 | — | — | US | disclosed |
| US-20140194412-A1 | THIOXOTHIAZOLIDINE DERIVATIVE HAVING RAS FUNCTION INHIBITORY EFFECT | KNC LABORATORIES CO., LTD. (JP) | 2014-07-10 | — | — | US | disclosed |
| US-20140194412-A1 | THIOXOTHIAZOLIDINE DERIVATIVE HAVING RAS FUNCTION INHIBITORY EFFECT | KNC LABORATORIES CO., LTD. (JP) | 2014-07-10 | — | — | US | disclosed |
| CN-102712202-A | Heat-sensitive lithographic printing plate and printing method thereof | MITSUBISHI PAPER MILLS LTD | 2012-10-03 | — | — | CN | disclosed |
| US-20120192740-A1 | FOUNTAIN SOLUTION COMPOSITION FOR LITHOGRAPHIC PRINTING PLATE AND LITHOGRAPHIC PRINTING METHOD | MITSUBISHI PAPER MILLS LIMITED (JP) | 2012-08-02 | — | — | US | disclosed |
| US-20100307359-A1 | HEAT-SENSITIVE LITHOGRAPHIC PRINTING PLATES | MITSUBISHI PAPER MILLS LIMITED (JP) | 2010-12-09 | — | — | US | disclosed |
| US-4808566-A | COLORLESS DYE IS DIMER OF 3-(4-SUBSTITUTED AMINOARYL)-3-(SUBSTITUTED INDOL-3-YL) PHTHALIDE | FUJI PHOTO FILM CO., LTD. (JP) | 1989-02-28 | — | — | US | disclosed |
| US-4803192-A | COLORLESS DYE, AN AMINOPHENYLINDOLYLPHTHALIDE AND AN ELECTRON ACCEPTOR | FUJI PHOTO FILM CO., LTD. (JP) | 1989-02-07 | — | — | US | disclosed |
| US-4800193-A | ANILINE, INDOLE AND PHTHALEIN DYES; COLORFASTNESS; AROMATIC SOLVENT-SOLUBLE | FUJI PHOTO FILM CO., LTD. (JP) | 1989-01-24 | — | — | US | disclosed |
| US-4771034-A | LEUCO DYE, SALICYCLIC ACID DERIVATIVE AS ELECTRON ACCEPTOR | FUJI PHOTO FILM CO., LTD. (JP) | 1988-09-13 | — | — | US | disclosed |
| EP-0262810-A2 | Sheet recording material containing dye-forming components | Fuji Photo Film Co., Ltd. (JP) | 1988-04-06 | — | — | EP | disclosed |
| EP-0141170-B1 | HEAT-SENSITIVE RECORDING MATERIAL | KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) | 1987-05-13 | — | — | EP | disclosed |
| EP-0219302-A2 | Recording materials | FUJI PHOTO FILM CO., LTD. (JP) | 1987-04-22 | — | — | EP | disclosed |
| US-4659643-A | A PHENOXY COMPOUND | KANZAKI PAPER MANUFACTURING CO. LTD. (JP) | 1987-04-21 | — | — | US | disclosed |
| US-4531140-A | Heat-sensitive recording material | Kansaki Paper Manufacturing Co. Ltd. (JP) | 1985-07-23 | — | — | US | disclosed |
| EP-0141170-A2 | Heat-sensitive recording material | KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) | 1985-05-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140194412-A1 | THIOXOTHIAZOLIDINE DERIVATIVE HAVING RAS FUNCTION INHIBITORY EFFECT | KRAS, NRAS, RASSF5 | DRD2 4040/4885DRD4 2977/4885DRD3 4133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.