Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.59 |
| ▸ | DRD2 | P14416 | 4/20 | 0.56 |
| ▸ | DRD4 | P21917 | 4/20 | 0.56 |
| ▸ | DRD3 | P35462 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12301160 | 0.86 | CYP1A2 (0.46) | L3MBTL1TDP1DRD2DRD4DRD3 | |
| SCHEMBL3763522 | 0.85 | DRD2 (0.73) | L3MBTL1TDP1DRD2DRD4DRD3 | |
| SCHEMBL5279270 | 0.85 | DRD2 (0.72) | L3MBTL1TDP1DRD2DRD4DRD3 | |
| SCHEMBL12301162 | 0.84 | TDP1 (0.69) | L3MBTL1TDP1DRD2DRD4DRD3 | |
| SCHEMBL386935 | 0.84 | L3MBTL1 (0.65) | L3MBTL1TDP1DRD2DRD4DRD3 | |
| SCHEMBL8067303 | 0.84 | L3MBTL1 (0.64) | L3MBTL1TDP1DRD2DRD4DRD3 | |
| SCHEMBL5289682 | 0.83 | TDP1 (0.56) | L3MBTL1TDP1DRD2DRD4DRD3 | |
| SCHEMBL1592876 | 0.82 | TDP1 (0.60) | L3MBTL1TDP1DRD2DRD4DRD3 | |
| SCHEMBL20005629 | 0.82 | SCN4A (0.55) | L3MBTL1MAPTCYP2C19CYP1A2CYP2D6 | |
| SCHEMBL3757321 | 0.82 | DRD2 (0.59) | L3MBTL1TDP1DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8022072-B2 | Azolylmethylidenehydrazine derivative and use thereof | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2011-09-20 | — | — | US | disclosed |
| US-8022072-B2 | Azolylmethylidenehydrazine derivative and use thereof | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2011-09-20 | — | — | US | disclosed |
| US-20100190754-A1 | AZOLYLMETHYLIDENEHYDRAZINE DERIVATIVE AND USE THEREOF | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2010-07-29 | — | — | US | disclosed |
| US-20100190754-A1 | AZOLYLMETHYLIDENEHYDRAZINE DERIVATIVE AND USE THEREOF | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2010-07-29 | — | — | US | disclosed |
| EP-2168951-A1 | AZOLYLMETHYLENEHYDRAZINE DERIVATIVE AND USE THEREOF | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2010-03-31 | — | — | EP | disclosed |
| WO-2006138653-A9 | THERMAL RECORDING MATERIALS AND METHODS OF MAKING AND USING THE SAME | NASHUA CORP (US) | 2007-03-01 | — | — | WO | disclosed |
| US-20060293181-A1 | Thermal recording materials and methods of making and using the same | NASHUA CORPORATION | 2006-12-28 | — | — | US | disclosed |
| WO-2006138653-A1 | THERMAL RECORDING MATERIALS AND METHODS OF MAKING AND USING THE SAME | NASHUA CORPORATION (US) | 2006-12-28 | — | — | WO | disclosed |
| US-RE36321-E | INCLUDING DIARYL DIETHER COMPOUND | KANSAKI PAPER MANUFACTURING CO., LTD. (JP) | 1999-09-28 | — | — | US | disclosed |
| EP-0141170-B1 | HEAT-SENSITIVE RECORDING MATERIAL | KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) | 1987-05-13 | — | — | EP | disclosed |
| US-4659643-A | A PHENOXY COMPOUND | KANZAKI PAPER MANUFACTURING CO. LTD. (JP) | 1987-04-21 | — | — | US | disclosed |
| US-4531140-A | Heat-sensitive recording material | Kansaki Paper Manufacturing Co. Ltd. (JP) | 1985-07-23 | — | — | US | disclosed |
| EP-0141170-A2 | Heat-sensitive recording material | KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) | 1985-05-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100190754-A1 | AZOLYLMETHYLIDENEHYDRAZINE DERIVATIVE AND USE THEREOF | ARSA, AHR, HRH2 | L3MBTL1 4420/4885TDP1 4865/4885DRD2 409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.