Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GCK | P35557 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3149260 | 0.87 | MEN1 (0.38) | MEN1KMT2AGCKGRM5RORC | |
| SCHEMBL534143 | 0.87 | MEN1 (0.38) | MEN1KMT2AGCKGRM5RORC | |
| SCHEMBL1412531 | 0.86 | MEN1 (0.39) | MEN1KMT2AGCKGRM5KDM4C | |
| SCHEMBL24167283 | 0.86 | MEN1 (0.44) | MEN1KMT2AGCKGRM5KDM4C | |
| SCHEMBL15273799 | 0.85 | MEN1 (0.39) | MEN1KMT2AGCKGRM5KDM4C | |
| SCHEMBL1412418 | 0.84 | MEN1 (0.38) | MEN1KMT2AGCKGRM5NPC1 | |
| SCHEMBL7188169 | 0.82 | MEN1 (0.37) | MEN1KMT2AGCKGRM5 | |
| SCHEMBL3040756 | 0.82 | MEN1 (0.36) | MEN1KMT2AGCKGRM5KDM4C | |
| SCHEMBL1513547 | 0.81 | MEN1 (0.36) | MEN1KMT2AGCKGRM5NPC1 | |
| SCHEMBL10576592 | 0.80 | MEN1 (0.38) | MEN1KMT2AGCKGRM5KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7846956-B2 | Malononitrile compound as pesticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-12-07 | — | — | US | disclosed |
| US-20090149425-A1 | Malononitrile compound as pesticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-06-11 | — | — | US | disclosed |
| EP-1704143-B1 | MALONONITRILE COMPOUND AS PESTICIDES | SUMITOMO CHEMICAL CO (JP) | 2008-09-03 | — | — | EP | disclosed |
| EP-1704143-A1 | MALONONITRILE COMPOUND AS PESTICIDES | Sumitomo Chemical Company, Limited (JP) | 2006-09-27 | — | — | EP | disclosed |
| WO-2005068432-A1 | MALONONITRILE COMPOUND AS PESTICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-07-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090149425-A1 | Malononitrile compound as pesticides | NR0B1, RTN4, OR10J3 | MEN1 929/4885KMT2A 3120/4885GCK 1358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.