Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GCK | P35557 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3040756 | 0.91 | MEN1 (0.36) | MEN1KMT2AGCKGRM5RORC | |
| SCHEMBL3763828 | 0.87 | MEN1 (0.39) | MEN1KMT2AGCKGRM5RORC | |
| SCHEMBL3149260 | 0.85 | MEN1 (0.38) | MEN1KMT2AGCKGRM5RORC | |
| SCHEMBL24167283 | 0.84 | MEN1 (0.44) | MEN1KMT2AGCKGRM5RORC | |
| SCHEMBL1412531 | 0.82 | MEN1 (0.39) | MEN1KMT2AGCKGRM5RORC | |
| SCHEMBL15273799 | 0.81 | MEN1 (0.39) | MEN1KMT2AGCKGRM5RORC | |
| SCHEMBL1412418 | 0.79 | MEN1 (0.38) | MEN1KMT2AGCKGRM5 | |
| SCHEMBL10576592 | 0.79 | MEN1 (0.38) | MEN1KMT2AGCKGRM5 | |
| SCHEMBL7188169 | 0.78 | MEN1 (0.37) | MEN1KMT2AGCKGRM5 | |
| SCHEMBL1513547 | 0.77 | MEN1 (0.36) | MEN1KMT2AGCKGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9340526-B2 | Process for preparing pyridyl-substituted pyrazoles | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-05-17 | — | — | US | disclosed |
| US-20150191447-A1 | Process for Preparing Pyridyl-Substituted Pyrazoles | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-07-09 | — | — | US | disclosed |
| US-8987460-B2 | Process for preparing pyridyl-substituted pyrazoles | BAYER CROPSCIENCE AG (DE) | 2015-03-24 | — | — | US | disclosed |
| EP-2414345-B1 | Method for manufacturing Pyridyl-substituted pyrazoles | BAYER CROPSCIENCE AG (DE) | 2014-09-17 | — | — | EP | disclosed |
| US-20130131347-A1 | Process for Preparing Pyridyl-Substituted Pyrazoles | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-05-23 | — | — | US | disclosed |
| US-8362261-B2 | Process for preparing pyridyl-substituted pyrazoles | BAYER CROPSCIENCE AG (DE) | 2013-01-29 | — | — | US | disclosed |
| US-20120136156-A2 | PROCESS FOR PREPARING PYRIDYL-SUBSTITUTED PYRAZOLES | BAYER CROPSCIENCE AG (DE) | 2012-05-31 | — | — | US | disclosed |
| EP-2414345-A1 | METHOD FOR PRODUCING PYRIDYL-SUBSTITUTED PYRAZOLES | Bayer CropScience AG (DE) | 2012-02-08 | — | — | EP | disclosed |
| US-20110087029-A1 | Process for Preparing Pyridyl-Substituted Pyrazoles | BAYER CROPSCIENCE AG (DE) | 2011-04-14 | — | — | US | disclosed |
| EP-2243777-A1 | Method for manufacturing Pyridyl-substituted pyrazoles | Bayer CropScience AG (DE) | 2010-10-27 | — | — | EP | disclosed |
| WO-2010112178-A1 | METHOD FOR PRODUCING PYRIDYL-SUBSTITUTED PYRAZOLES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2010-10-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130131347-A1 | Process for Preparing Pyridyl-Substituted Pyrazoles | PDXK, PLK2, WNK3 | MEN1 3529/4885KMT2A 3361/4885GCK 29/4885 |
| US-20150191447-A1 | Process for Preparing Pyridyl-Substituted Pyrazoles | PDXK, PLK2, WNK3 | MEN1 3529/4885KMT2A 3361/4885GCK 29/4885 |
| US-20110087029-A1 | Process for Preparing Pyridyl-Substituted Pyrazoles | PDXK, PLK2, WNK3 | MEN1 3529/4885KMT2A 3361/4885GCK 29/4885 |
| US-20120136156-A2 | PROCESS FOR PREPARING PYRIDYL-SUBSTITUTED PYRAZOLES | PDXK, PLK2, WNK3 | MEN1 3529/4885KMT2A 3361/4885GCK 29/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.