SCHEMBL3764030

SCHEMBL3764030

CC1CCCCC(CCCC(=O)O)(C(=O)O)C1

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.44
CYP2C19 P33261 1/20 0.40
BBOX1 O75936 2/20 0.33
PTGS1 P23219 2/20 0.33
CYP4F2 P78329 3/20 0.33
CYP4A11 Q02928 3/20 0.33
ALDH1A1 P00352 1/20 0.33
TBXAS1 P24557 2/20 0.32
EPHX2 P34913 1/20 0.32
UGT2B7 P16662 1/20 0.32
EPHX1 P07099 1/20 0.31
MME P08473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4539487 0.90 CYP1A2 (0.46) CYP1A2CYP2C19PTGS1CYP4F2CYP4A11
SCHEMBL277802 0.89 CYP1A2 (0.40) CYP1A2CYP2C19BBOX1PTGS1ALDH1A1
Ethylene Glycol SCHEMBL7148634 0.85 CYP1A2 (0.37) CYP1A2BBOX1PTGS1
SCHEMBL2159793 0.82 LMNA (0.37) CYP1A2ALDH1A1
SCHEMBL27313919 0.80 CYP1A2 (0.45) CYP1A2CYP2C19CYP4F2CYP4A11TBXAS1
SCHEMBL220706 0.80 CYP2C19 (0.54) CYP1A2CYP2C19BBOX1CYP4F2CYP4A11
SCHEMBL11770353 0.80 CYP2C19 (0.61) CYP1A2CYP2C19ALDH1A1MME
SCHEMBL11773361 0.80 CYP2C19 (0.61) CYP1A2CYP2C19ALDH1A1MME
SCHEMBL15106900 0.79 CYP1A2 (0.35) CYP1A2CYP2C19ALDH1A1
SCHEMBL220603 0.78 CYP2C19 (0.57) CYP1A2CYP2C19CYP4F2CYP4A11ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100015452-A1 COMPOSITE ARTICLE PROVIDING BLAST MITIGATION AND METHOD FOR MANUFACTURING SAME PPG INDUSTRIES OHIO, INC. 2010-01-21 US disclosed
EP-0164523-B1 TIRES AND WHEELS FROM LOW HEAT BUILDUP POLYURETHANE COMPOSITIONS AIR PRODUCTS AND CHEMICALS, INC. (US) 1991-09-04 EP disclosed
US-4786703-A FREE OF OLIGOMERS AND UNREACTED DIISOCYANATE AIR PRODUCTS AND CHEMICALS, INC. (US) 1988-11-22 US disclosed
EP-0164523-A1 Tires and wheels from low heat buildup polyurethane compositions AIR PRODUCTS AND CHEMICALS, INC. (US) 1985-12-18 EP disclosed
US-4556703-A Low heat buildup polyurethane compositions and articles AMERICAN CYANAMID COMPANY (US) 1985-12-03 US disclosed