Ethylene Glycol

Ethylene Glycol

SCHEMBL7148634

CC1CCC(CCCC(=O)O)(C(=O)O)C1.OCCO

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.37
CAMK2A Q9UQM7 1/20 0.34
GPR84 Q9NQS5 1/20 0.32
FFAR1 O14842 1/20 0.32
FFAR4 Q5NUL3 1/20 0.32
PTGS1 P23219 1/20 0.31
BBOX1 O75936 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL277802 0.95 CYP1A2 (0.40) CYP1A2GPR84FFAR1FFAR4PTGS1
Ethylene Glycol SCHEMBL4613517 0.91 CAMK2A (0.36) CYP1A2CAMK2AGPR84FFAR1FFAR4
SCHEMBL15106900 0.85 CYP1A2 (0.35) CYP1A2GPR84FFAR1FFAR4
SCHEMBL3764030 0.85 CYP1A2 (0.44) CYP1A2PTGS1BBOX1
SCHEMBL2159793 0.82 LMNA (0.37) CYP1A2GPR84FFAR1FFAR4
SCHEMBL4539487 0.81 CYP1A2 (0.46) CYP1A2GPR84FFAR1FFAR4PTGS1
Ethylene Glycol SCHEMBL6051015 0.78 CAMK2A (0.52) CYP1A2CAMK2AGPR84FFAR1FFAR4
Ethylene Glycol SCHEMBL4414824 0.78 CAMK2A (0.37) CAMK2AGPR84FFAR1FFAR4
SCHEMBL22098195 0.77 CYP4F2 (0.38) CYP1A2
Ethylene Glycol SCHEMBL250392 0.75 CYP2C19 (0.48) CYP1A2CAMK2AGPR84FFAR1FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030225240-A1 Modified urethane compositions containing adducts of O-phthalic anhydride ester polyols UNIROYAL CHEMICAL COMPANY, INC. 2003-12-04 US disclosed
WO-2002004536-A2 MODIFIED URETHANE COMPOSITIONS CONTAINING ADDUCTS OF O-PHTHALIC ANHYDRIDE ESTER POLYOLS UNIROYAL CHEMICAL COMPANY, INC. (US) 2002-01-17 WO disclosed
EP-0171085-A2 Vulcanized rubber article and the process for production thereof KURARAY CO., LTD. (JP) 1986-02-12 EP disclosed