SCHEMBL2159793

SCHEMBL2159793

CC1CC(CCCC(=O)O)(C(=O)O)C1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.37
SLC22A6 Q4U2R8 2/20 0.37
TSHR P16473 5/20 0.36
NFKB1 P19838 1/20 0.36
PMP22 Q01453 1/20 0.36
AKR1B1 P15121 1/20 0.35
GPR84 Q9NQS5 7/20 0.34
PPARG P37231 7/20 0.34
PPARD Q03181 7/20 0.34
PPARA Q07869 7/20 0.34
HDAC11 Q96DB2 5/20 0.34
PTPN1 P18031 3/20 0.34
ALDH1A1 P00352 2/20 0.34
TLR2 O60603 2/20 0.34
TDP1 Q9NUW8 2/20 0.34
FABP4 P15090 2/20 0.34
SLC22A8 Q8TCC7 1/20 0.34
MEN1 O00255 1/20 0.34
ESR1 P03372 1/20 0.34
ALOX15 P16050 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2148219 0.88 CYP1A2 (0.35) LMNACYP1A2
SCHEMBL277802 0.86 CYP1A2 (0.40) LMNASLC22A6TSHRNFKB1PMP22
Ethylene Glycol SCHEMBL7148634 0.82 CYP1A2 (0.37) GPR84FFAR1FFAR4CYP1A2
SCHEMBL3764030 0.82 CYP1A2 (0.44) ALDH1A1CYP1A2
SCHEMBL15106900 0.81 CYP1A2 (0.35) LMNASLC22A6TSHRNFKB1PMP22
Ethylene Glycol SCHEMBL4613517 0.78 CAMK2A (0.36) LMNASLC22A6TSHRNFKB1PMP22
SCHEMBL4539487 0.77 CYP1A2 (0.46) LMNASLC22A6TSHRNFKB1PMP22
SCHEMBL249726 0.77 CAMK2A (0.46) LMNASLC22A6TSHRNFKB1PMP22
SCHEMBL8527125 0.74 LMNA (0.39) LMNASLC22A6TSHRNFKB1PMP22
SCHEMBL250313 0.74 LMNA (0.39) LMNASLC22A6TSHRNFKB1PMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10377847-B2 Strong reversible hydrogels SUPRAPOLIX B.V. (NL) 2019-08-13 US disclosed
EP-1773903-B1 SUPRAMOLECULAR IONOMERS SUPRAPOLIX BV (NL) 2017-08-09 EP disclosed
EP-2343342-B1 STRONG REVERSIBLE HYDROGELS SUPRAPOLIX BV (NL) 2015-09-16 EP disclosed
US-9006364-B2 Supramolecular polymers from low-melting, easily processable building blocks SUPRAPOLIX B.V. (NL) 2015-04-14 US disclosed
US-20140142256-A1 SUPRAMOLECULAR POLYMERS FROM LOW-MELTING, EASILY PROCESSABLE BUILDING BLOCKS SUPRAPOLIX B.V. (NL) 2014-05-22 US disclosed
US-20140128482-A1 STRONG REVERSIBLE HYDROGELS SUPRAPOLIX B.V. (NL) 2014-05-08 US disclosed
US-8628789-B2 Strong reversible hydrogels SUPRAPOLIX, B.V. (NL) 2014-01-14 US disclosed
US-8268952-B2 Supramolecular ionomers SUPRAPOLIX B.V. (NL) 2012-09-18 US disclosed
EP-2087027-B1 SUPRAMOLECULAR POLYMERS FROM LOW-MELTING, EASILY PROCESSABLE BUILDING BLOCKS SUPRAPOLIX BV (NL) 2011-10-05 EP disclosed
EP-2343342-A1 Strong reversible hydrogels SupraPolix B.V. (NL) 2011-07-13 EP disclosed
EP-1972661-B1 Strong reversible hydrogels SUPRAPOLIX BV (NL) 2011-07-06 EP disclosed
US-20100076147-A1 SUPRAMOLECULAR POLYMERS FROM LOW-MELTING, EASILY PROCESSABLE BUILDING BLOCKS SUPRAPOLIX B.V. (NL) 2010-03-25 US disclosed
US-20090297714-A1 FLUSH PIGMENT FOR SOLID INKJET INK XEROX CORPORATION (US) 2009-12-03 US disclosed
EP-2087027-A2 SUPRAMOLECULAR POLYMERS FROM LOW-MELTING, EASILY PROCESSABLE BUILDING BLOCKS SupraPolix B.V. (NL) 2009-08-12 EP disclosed
US-20090111930-A1 Supramolecular Ionomers SUPRAPOLIX B. V. 2009-04-30 US disclosed
US-20080260795-A1 STRONG REVERSIBLE HYDROGELS SUPRAPOLIX B.V. 2008-10-23 US disclosed
EP-1972661-A1 Strong reversible hydrogels SupraPolix B.V. (NL) 2008-09-24 EP disclosed
WO-2008063057-A2 SUPRAMOLECULAR POLYMERS FROM LOW-MELTING, EASILY PROCESSABLE BUILDING BLOCKS SUPRAPOLIX B.V. (NL) 2008-05-29 WO disclosed
EP-1773903-A1 SUPRAMOLECULAR IONOMERS SupraPolix B.V. (NL) 2007-04-18 EP disclosed
WO-2006006855-A1 SUPRAMOLECULAR IONOMERS SUPRAPOLIX B.V. (NL) 2006-01-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10377847-B2 Strong reversible hydrogels HSPA4L, H1-4, CD44 LMNA 3849/4885SLC22A6 3083/4885TSHR 4594/4885
US-20080260795-A1 STRONG REVERSIBLE HYDROGELS HSPA4L, H1-4, CD44 LMNA 3849/4885SLC22A6 3083/4885TSHR 4594/4885
US-20140128482-A1 STRONG REVERSIBLE HYDROGELS HSPA4L, H1-4, CD44 LMNA 3849/4885SLC22A6 3083/4885TSHR 4594/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.