Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.38 |
| ▸ | F2R | P25116 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3662523 | 1.00 | NPC1 (0.39) | NPC1RAB9AHPGDMAPTHTT | |
| SCHEMBL3769663 | 0.90 | NFE2L2 (0.41) | NPC1RAB9AHPGDMAPTHTT | |
| SCHEMBL3662395 | 0.90 | NFE2L2 (0.38) | NPC1RAB9AHPGDMAPTHTT | |
| SCHEMBL3776287 | 0.90 | NFE2L2 (0.38) | NPC1RAB9AHPGDMAPTHTT | |
| SCHEMBL3662353 | 0.90 | NFE2L2 (0.41) | NPC1RAB9AHPGDMAPTHTT | |
| SCHEMBL3662246 | 0.87 | MDM2 (0.40) | NPC1RAB9AHPGDMAPTHTT | |
| SCHEMBL3762718 | 0.87 | MDM2 (0.40) | NPC1RAB9AHPGDMAPTHTT | |
| SCHEMBL3662316 | 0.84 | ABCG2 (0.44) | NPC1RAB9AMAPTSMN1; SMN2KMT2A | |
| SCHEMBL3662315 | 0.84 | ABCG2 (0.44) | NPC1RAB9AMAPTSMN1; SMN2KMT2A | |
| SCHEMBL3769358 | 0.84 | TRPA1 (0.39) | NPC1RAB9AHPGDMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100317515-A1 | Azolylmethyloxiranes, use Thereof and Agents Containing the Same | BASF SE (DE) | 2010-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317515-A1 | Azolylmethyloxiranes, use Thereof and Agents Containing the Same | XDH, NOX5, TET1 | NPC1 4668/4885RAB9A 4287/4885HPGD 174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.