SCHEMBL3764264

SCHEMBL3764264

CCc1c(N)c(CC)c(C2CCCCC2)c(N)c1CC1CCCCC1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
NOS1 P29475 2/20 0.32
NOS2 P35228 2/20 0.32
NOS3 P29474 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4539596 0.81 CNR1 (0.32) NOS1NOS2NOS3
SCHEMBL3428803 0.79 NOS3 (0.31) NOS1NOS2NOS3
SCHEMBL3396922 0.75
SCHEMBL3423940 0.71 CNR1 (0.32)
SCHEMBL3425985 0.69 CNR1 (0.35) NOS1NOS2NOS3
SCHEMBL9722016 0.69 EPHX2 (0.34) NOS1NOS2NOS3
SCHEMBL3399225 0.67 EPHX2 (0.34) NOS1NOS2NOS3
SCHEMBL3392968 0.67 CNR1 (0.33)
SCHEMBL3394722 0.65 GABRA1 (0.33) NOS1NOS2NOS3
SCHEMBL1499472 0.65 CNR1 (0.38) NOS1NOS2NOS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2240559-A2 CYCLOALKYL PHENYLENEDIAMINES AS DEPOSIT CONTROL AGENTS FOR LUBRICANTS Chemtura Corporation (US) 2010-10-20 EP disclosed
US-20090156441-A1 Cycloalkyl phenylenediamines as deposit control agents for lubricants GREAT LAKES CHEMICAL GLOBAL, INC. 2009-06-18 US disclosed
WO-2009076090-A2 CYCLOALKYL PHENYLENEDIAMINES AS DEPOSIT CONTROL AGENTS FOR LUBRICANTS CHEMTURA CORPORATION (US) 2009-06-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090156441-A1 Cycloalkyl phenylenediamines as deposit control agents for lubricants C5, C9, C1S NOS1 2418/4885NOS2 2516/4885NOS3 2171/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.