SCHEMBL4539596

SCHEMBL4539596

CCc1c(N)c(C2CCCCC2)c(N)c(CC)c1C1CCCCC1

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 5/20 0.32
CNR2 P34972 4/20 0.32
NOS3 P29474 1/20 0.31
NOS1 P29475 1/20 0.31
NOS2 P35228 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3428803 0.98 NOS3 (0.31) CNR1CNR2NOS3NOS1NOS2
SCHEMBL3396922 0.89
SCHEMBL3399225 0.84 EPHX2 (0.34) CNR1CNR2NOS3NOS1NOS2
SCHEMBL3394722 0.82 GABRA1 (0.33) CNR1CNR2NOS3NOS1NOS2
SCHEMBL3423940 0.81 CNR1 (0.32) CNR1CNR2
SCHEMBL1499472 0.81 CNR1 (0.38) CNR1CNR2NOS3NOS1NOS2
SCHEMBL3764264 0.81 NOS1 (0.32) NOS3NOS1NOS2
SCHEMBL3395246 0.79 CNR1 (0.36) CNR1CNR2NOS1NOS2
SCHEMBL3424412 0.79
SCHEMBL9722016 0.78 EPHX2 (0.34) CNR1CNR2NOS3NOS1NOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2245123-B1 METHODS FOR PRODUCING ALKYLATED 1,3 BENZENEDIAMINE COMPOUNDS CHEMTURA CORP (US) 2017-07-19 EP disclosed
US-8563489-B2 Alkylated 1,3-benzenediamine compounds and methods for producing same CHEMTURA CORPORATION (US) 2013-10-22 US disclosed
US-20090156449-A1 ALKYLATED 1,3-BENZENEDIAMINE COMPOUNDS AND METHODS FOR PRODUCING SAME LANXESS SOLUTIONS US INC. 2009-06-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090156449-A1 ALKYLATED 1,3-BENZENEDIAMINE COMPOUNDS AND METHODS FOR PRODUCING SAME BBOX1, ABHD5, BRD1 CNR1 1089/4885CNR2 1027/4885NOS3 1850/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.