Tembotrione

Tembotrione

SCHEMBL3764538

CCc1ccc2nc(C)c(S(=O)(=O)NC(=O)Nc3nc(OC)cc(OC)n3)n2n1.CS(=O)(=O)c1ccc(C(=O)C2C(=O)CCCC2=O)c(Cl)c1COCC(F)(F)F

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.32
CDK1 P06493 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3767478 0.89
Rimsulfuron SCHEMBL19463538 0.80 GAA (0.34) GAACDK1
Nicosulfuron SCHEMBL19463457 0.79 CDK1 (0.40) GAACDK1
Tembotrione SCHEMBL3768470 0.78 GAA (0.30) GAACDK1
Foramsulfuron SCHEMBL19463650 0.78 CDK1 (0.60) GAACDK1
Tembotrione SCHEMBL3801648 0.77 GAA (0.32) GAACDK1
SCHEMBL3343785 0.76 GAA (0.49) GAACDK1
Tembotrione SCHEMBL3802927 0.75 CDK1 (0.32) GAACDK1
Tembotrione SCHEMBL3225813 0.74 HPD (0.38) GAA
Tembotrione SCHEMBL116424 0.74 HPD (0.38) GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8492313-B2 Synergistic herbicidal combinations comprising tembotrione BAYER CROPSCIENCE AG (DE) 2013-07-23 US disclosed
US-20100311588-A1 SYNERGISTIC HERBICIDAL COMBINATIONS COMPRISING TEMBOTRIONE BAYER CROPSCIENCE AG (DE) 2010-12-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100311588-A1 SYNERGISTIC HERBICIDAL COMBINATIONS COMPRISING TEMBOTRIONE DDT, TUBB, TUBB3 GAA 378/4885CDK1 4040/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.