Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | INSR | P06213 | 1/20 | 0.34 |
| ▸ | IGF1R | P08069 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7994052 | 0.81 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL8388696 | 0.81 | ALDH1A1 (0.40) | ALDH1A1MAPK14INSRIGF1RFGFR1 | |
| SCHEMBL3765271 | 0.79 | NOTUM (0.43) | ALDH1A1MAPK14EGFRINSRIGF1R | |
| SCHEMBL11607136 | 0.79 | ALDH1A1 (0.39) | ALDH1A1MAPK14INSRIGF1RFGFR1 | |
| SCHEMBL15199527 | 0.79 | ALDH1A1 (0.39) | ALDH1A1MAPK14INSRIGF1RFGFR1 | |
| SCHEMBL7982124 | 0.79 | ALDH1A1 (0.34) | ALDH1A1MEN1KMT2A | |
| SCHEMBL2271449 | 0.79 | NOTUM (0.43) | ALDH1A1MAPK14INSRIGF1RFGFR1 | |
| SCHEMBL16939227 | 0.78 | RAB9A (0.42) | ALDH1A1MEN1KMT2A | |
| SCHEMBL7992500 | 0.78 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL21325315 | 0.76 | ALDH1A1 (0.37) | ALDH1A1MAPK14INSRIGF1RFGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113004214-A | Synthesis method of high-purity 3-tert-butyl-5- (chloromethyl) isoxazole | 苏州健雄职业技术学院 | 2021-06-22 | — | — | CN | claimed |
| CN-113004214-A | Synthesis method of high-purity 3-tert-butyl-5- (chloromethyl) isoxazole | 苏州健雄职业技术学院 | 2021-06-22 | — | — | CN | disclosed |
| CN-113004214-A | Synthesis method of high-purity 3-tert-butyl-5- (chloromethyl) isoxazole | 苏州健雄职业技术学院 | 2021-06-22 | — | — | CN | disclosed |
| CN-113004214-A | Synthesis method of high-purity 3-tert-butyl-5- (chloromethyl) isoxazole | 苏州健雄职业技术学院 | 2021-06-22 | — | — | CN | disclosed |
| US-7846956-B2 | Malononitrile compound as pesticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-12-07 | — | — | US | disclosed |
| US-7846956-B2 | Malononitrile compound as pesticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-12-07 | — | — | US | disclosed |
| US-7846956-B2 | Malononitrile compound as pesticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-12-07 | — | — | US | disclosed |
| US-20090149425-A1 | Malononitrile compound as pesticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-06-11 | — | — | US | disclosed |
| US-20090149425-A1 | Malononitrile compound as pesticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-06-11 | — | — | US | disclosed |
| US-20090149425-A1 | Malononitrile compound as pesticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-06-11 | — | — | US | disclosed |
| EP-1704143-B1 | MALONONITRILE COMPOUND AS PESTICIDES | SUMITOMO CHEMICAL CO (JP) | 2008-09-03 | — | — | EP | disclosed |
| EP-1704143-B1 | MALONONITRILE COMPOUND AS PESTICIDES | SUMITOMO CHEMICAL CO (JP) | 2008-09-03 | — | — | EP | disclosed |
| EP-1704143-A1 | MALONONITRILE COMPOUND AS PESTICIDES | Sumitomo Chemical Company, Limited (JP) | 2006-09-27 | — | — | EP | disclosed |
| WO-2005068432-A1 | MALONONITRILE COMPOUND AS PESTICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-07-28 | — | — | WO | disclosed |
| EP-0010166-B1 | N-(1,2-AZOLYL)ALKYL-CHLOROACETANILIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES | BAYER AG (DE) | 1982-10-27 | — | — | EP | disclosed |
| EP-0002480-B1 | PROCESS FOR PREPARATION OF 1,2-OXAZOLE DERIVATIVES | BASF Aktiengesellschaft (DE) | 1982-06-09 | — | — | EP | disclosed |
| US-4256480-A | Isoxazolyl-alkyl thiocarbamates and herbicidal compositions thereof | PHILAGRO (FR) | 1981-03-17 | — | — | US | disclosed |
| EP-0010166-A1 | N-(1,2-Azolyl)alkyl-chloroacetanilides, process for their preparation and their use as herbicides | BAYER AG (DE) | 1980-04-30 | — | — | EP | disclosed |
| EP-0002480-A1 | Process for preparation of 1,2-oxazole derivatives | BASF Aktiengesellschaft (DE) | 1979-06-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090149425-A1 | Malononitrile compound as pesticides | NR0B1, RTN4, OR10J3 | ALDH1A1 2751/4885MAPK14 1777/4885EGFR 2255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.