SCHEMBL3765267

SCHEMBL3765267

COc1ccc(/C=C/C(=O)NCCc2ccc(I)c(S(N)(=O)=O)c2)c(OC)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LY96 Q9Y6Y9 1/20 0.62
MAPT P10636 7/20 0.53
ALDH1A1 P00352 4/20 0.53
CA12 O43570 1/20 0.53
CA1 P00915 1/20 0.53
CA2 P00918 1/20 0.53
CA9 Q16790 1/20 0.53
LMNA P02545 2/20 0.50
HPGD P15428 1/20 0.50
HTT P42858 1/20 0.50
KDM4E B2RXH2 3/20 0.48
PKM P14618 1/20 0.48
ACHE P22303 3/20 0.47
TYR P14679 1/20 0.47
BCHE P06276 1/20 0.47
HDAC8 Q9BY41 1/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
POLB P06746 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3775827 1.00 LY96 (0.62) LY96MAPTALDH1A1CA12CA1
SCHEMBL7108281 0.92 LY96 (0.65) LY96MAPTALDH1A1CA12CA1
SCHEMBL7108279 0.92 LY96 (0.65) LY96MAPTALDH1A1CA12CA1
SCHEMBL7109497 0.86 LY96 (0.58) LY96MAPTALDH1A1CA12CA1
SCHEMBL7657276 0.86 LY96 (0.58) LY96MAPTALDH1A1CA12CA1
SCHEMBL7115603 0.86 LY96 (0.58) LY96MAPTALDH1A1CA12CA1
SCHEMBL7115605 0.86 LY96 (0.58) LY96MAPTALDH1A1CA12CA1
SCHEMBL7657277 0.86 LY96 (0.58) LY96MAPTALDH1A1CA12CA1
SCHEMBL7109500 0.86 LY96 (0.58) LY96MAPTALDH1A1CA12CA1
SCHEMBL7663052 0.85 LY96 (0.55) LY96MAPTALDH1A1CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1717228-A1 Sulfonylamino(thio)carbonylderivatives as herbicides or plant growth regulators Bayer CropScience GmbH (DE) 2006-11-02 EP claimed
US-7855166-B2 Sulfonylamino(thio)carbonyl compounds BAYER CROPSCIENCE GMBH (DE) 2010-12-21 US disclosed
EP-1877380-A1 SULFONYLAMINO(THIO)CARBONYL COMPOUNDS IN THE FORM OF HERBICIDES OR PLANT GROWTH REGULATORS BAYER CROPSCIENCE AG (DE) 2008-01-16 EP disclosed
US-20060258536-A1 Sulfonylamino(thio)carbonyl compounds BAYER CROPSCIENCE GMBH (DE) 2006-11-16 US disclosed
EP-1717228-A1 Sulfonylamino(thio)carbonylderivatives as herbicides or plant growth regulators Bayer CropScience GmbH (DE) 2006-11-02 EP disclosed
WO-2006114221-A1 SULFONYLAMINO(THIO)CARBONYL COMPOUNDS IN THE FORM OF HERBICIDES OR PLANT GROWTH REGULATORS BAYER CROPSCIENCE AG (DE) 2006-11-02 WO disclosed
EP-1183236-B1 CINNAMOYLAMINOALKYL-SUBSTITUTED BENZENESULFONAMIDE DERIVATIVES AVENTIS PHARMA GMBH (DE) 2003-10-22 EP disclosed
EP-1183236-A1 CINNAMOYLAMINOALKYL-SUBSTITUTED BENZENESULFONAMIDE DERIVATIVES Aventis Pharma Deutschland GmbH (DE) 2002-03-06 EP disclosed
US-6350778-B1 CARDIOVASCULAR DISORDERS AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2002-02-26 US disclosed
WO-2000071513-A1 CINNAMOYLAMINOALKYL-SUBSTITUTED BENZENESULFONAMIDE DERIVATIVES AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2000-11-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060258536-A1 Sulfonylamino(thio)carbonyl compounds TST, CBR3, MYB LY96 3412/4885MAPT 3054/4885ALDH1A1 1134/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.