SCHEMBL3765289

SCHEMBL3765289

C=Cc1ccc(Cc2nnc(S)s2)cc1

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.39
LMNA P02545 4/20 0.36
HPGD P15428 2/20 0.36
KMT2A Q03164 3/20 0.33
POLB P06746 3/20 0.33
MEN1 O00255 2/20 0.33
HTT P42858 1/20 0.33
MAPT P10636 2/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31
HSD17B10 Q99714 1/20 0.31
TSHR P16473 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
F2R P25116 1/20 0.30
ABL1 P00519 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3907570 0.82 ALDH1A1 (0.38) ALDH1A1LMNAHPGDKMT2APOLB
SCHEMBL2211930 0.77 ALDH1A1 (0.61) ALDH1A1LMNAKMT2APOLBMEN1
SCHEMBL490778 0.73 NPC1 (0.43) ALDH1A1LMNAHPGDKMT2AMEN1
SCHEMBL3765291 0.71 ALDH1A1 (0.33) ALDH1A1MAPTNPC1RAB9A
SCHEMBL50300 0.71 ALDH1A1 (0.65) ALDH1A1LMNAHPGDKMT2APOLB
SCHEMBL32670784 0.65 ALDH1A1 (0.55) ALDH1A1LMNAKMT2APOLBMEN1
SCHEMBL1562120 0.64 ALDH1A1 (0.59) ALDH1A1LMNAPOLBTSHR
SCHEMBL4452397 0.63 SLC5A2 (0.42) ALDH1A1LMNAPOLBTSHR
SCHEMBL171622 0.63 ALDH1A1 (0.58) ALDH1A1LMNAKMT2APOLBMEN1
SCHEMBL28858334 0.62 ALDH1A1 (0.50) ALDH1A1LMNAPOLBTSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8361701-B2 Method for making lithographic plates EASTMAN KODAK COMPANY (US) 2013-01-29 US disclosed
US-20100304304-A1 METHOD FOR MAKING LITHOGRAPHIC PLATES KODAK PHILIPPINES LTD. 2010-12-02 US disclosed
EP-2040124-A1 Method for making lithographic printing plates EASTMAN KODAK COMPANY (US) 2009-03-25 EP disclosed
EP-1849042-B1 PROCESS FOR THE PRODUCTION OF LITHOGRAPHIC PRINTING PLATES KODAK GRAPHIC COMM GMBH (DE) 2008-12-10 EP disclosed
US-20080145790-A1 Process for Production of Lithographic Printing Plates KODAK POLYCHROME GRAPHICS, GMBH (DE) 2008-06-19 US disclosed