SCHEMBL490778

SCHEMBL490778

C=Cc1ccc(CSc2nnc(S)s2)cc1

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.43
RAB9A P51151 4/20 0.43
LMNA P02545 5/20 0.41
HPGD P15428 1/20 0.41
ALDH1A1 P00352 5/20 0.40
MAPT P10636 3/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
HTT P42858 2/20 0.39
TP53 P04637 1/20 0.39
TERT O14746 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.37
FFAR1 O14842 1/20 0.37
GSK3B P49841 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2C19 P33261 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6393160 0.89 LMNA (0.50) NPC1RAB9ALMNAHPGDALDH1A1
SCHEMBL12058190 0.83 NPC1 (0.48) NPC1RAB9ALMNAHPGDALDH1A1
SCHEMBL21693343 0.82 RAB9A (0.66) NPC1RAB9ALMNAHPGDALDH1A1
SCHEMBL13922023 0.82 NPC1 (0.47) NPC1RAB9ALMNAHPGDALDH1A1
SCHEMBL9277488 0.82 NPC1 (0.47) NPC1RAB9ALMNAHPGDALDH1A1
SCHEMBL1720545 0.79 LMNA (0.58) NPC1RAB9ALMNAHPGDALDH1A1
SCHEMBL1104224 0.76 RAB9A (0.42) NPC1RAB9ALMNAHPGDALDH1A1
SCHEMBL10089270 0.75 NPC1 (0.41) NPC1RAB9ALMNAHPGDALDH1A1
SCHEMBL9479429 0.75 LMNA (0.74) NPC1RAB9ALMNAHPGDALDH1A1
SCHEMBL3765289 0.73 ALDH1A1 (0.39) NPC1RAB9ALMNAHPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-8165438-A None JP disclosed
US-10969685-B2 Photoresist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2021-04-06 US disclosed
EP-3130465-B1 HEAT-SENSITIVE LITHOGRAPHIC PRINTING PLATE PRECURSOR AGFA NV (BE) 2020-05-13 EP disclosed
EP-3130465-B1 HEAT-SENSITIVE LITHOGRAPHIC PRINTING PLATE PRECURSOR AGFA NV (BE) 2020-05-13 EP disclosed
US-20180236759-A1 HEAT-SENSITIVE LITHOGRAPHIC PRINTING PLATE PRECURSOR AGFA NV (BE) 2018-08-23 US disclosed
WO-2017025307-A1 HEAT-SENSITIVE LITHOGRAPHIC PRINTING PLATE PRECURSOR AGFA GRAPHICS NV (BE) 2017-02-16 WO disclosed
WO-2017025307-A1 HEAT-SENSITIVE LITHOGRAPHIC PRINTING PLATE PRECURSOR AGFA GRAPHICS NV (BE) 2017-02-16 WO disclosed
EP-3130465-A1 HEAT-SENSITIVE LITHOGRAPHIC PRINTING PLATE PRECURSOR AGFA GRAPHICS NV (BE) 2017-02-15 EP disclosed
EP-3130465-A1 HEAT-SENSITIVE LITHOGRAPHIC PRINTING PLATE PRECURSOR AGFA GRAPHICS NV (BE) 2017-02-15 EP disclosed
US-20150086927-A1 PHOTORESIST COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-03-26 US disclosed
EP-2028548-A1 Processing of lithographic printing plates with a developer solution containing a hydrophilic polymer EASTMAN KODAK COMPANY (US) 2009-02-25 EP disclosed
US-20090011363-A1 Photopolymer Composition Usable for Lithographic Plates BANK OF AMERICA, N.A., AS AGENT 2009-01-08 US disclosed
US-20080311524-A1 Method For Making Negative-Working Heat-Sensitive Lithographic Printing Plate Precursor AGFA GRAPHICS N.V. (BE) 2008-12-18 US disclosed
US-20080311524-A1 Method For Making Negative-Working Heat-Sensitive Lithographic Printing Plate Precursor AGFA GRAPHICS N.V. (BE) 2008-12-18 US disclosed
US-20080248424-A1 Photopolymer Composition Suitable for Lithographic Printing Plates BANK OF AMERICA, N.A., AS AGENT 2008-10-09 US disclosed
EP-1903399-A1 Method for developing and sealing of lithographic printing plates EASTMAN KODAK COMPANY (US) 2008-03-26 EP disclosed
EP-1868036-A1 Method for processing of photopolymer printing plates with overcoat EASTMAN KODAK COMPANY (US) 2007-12-19 EP disclosed
US-6866981-B2 Mixture of cationic polymer containing unsaturated aromatic compound and sulfonated aromatic compound, photoinitiator and acid generator MITSUBISHI PAPER MILLS LIMITED (JP) 2005-03-15 US disclosed
US-20030190548-A1 Mixture of cationic polymer containing unsaturated aromatic compound and sulfonated aromatic compound, photoinitiator and acid generator MITSUBISHI PAPER MILLS LIMITED (JP) 2003-10-09 US disclosed
JP-H08165438-A ANTISTATIC AGENT MITSUBISHI PAPER MILLS LTD 1996-06-25 JP disclosed