Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.36 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32670784 | 0.92 | ALDH1A1 (0.55) | ALDH1A1TSHRTDP1CYP3A4ESR1 | |
| SCHEMBL1562120 | 0.90 | ALDH1A1 (0.59) | ALDH1A1TSHRCALM1PSMD14LMNA | |
| SCHEMBL28858334 | 0.88 | ALDH1A1 (0.50) | ALDH1A1TSHRTDP1CYP3A4ESR1 | |
| SCHEMBL18545502 | 0.88 | ALDH1A1 (0.50) | ALDH1A1TSHRTDP1CYP3A4HDAC8 | |
| SCHEMBL7779425 | 0.84 | CA2 (0.46) | ALDH1A1TSHRTDP1ESR1ESR2 | |
| SCHEMBL595507 | 0.82 | TP53 (0.45) | ALDH1A1TSHRTDP1CALM1PSMD14 | |
| SCHEMBL14029956 | 0.82 | LTA4H (0.59) | ALDH1A1TSHRCYP3A4LMNALTA4H | |
| SCHEMBL2735720 | 0.82 | ALDH1A1 (0.44) | ALDH1A1TSHRTDP1CYP3A4ESR1 | |
| SCHEMBL13871137 | 0.82 | LOXL2 (0.48) | ALDH1A1LMNAKMT2ASMN1; SMN2CA1 | |
| SCHEMBL8740584 | 0.82 | ALDH1A1 (0.68) | ALDH1A1TSHRTDP1CYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 367 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12570784-B2 | Method for making embedded hydrogel contact lenses | ALCON INC. (CH) | 2026-03-10 | — | — | US | claimed |
| US-12539650-B2 | Method for making embedded hydrogel contact lenses | ALCON INC. (CH) | 2026-02-03 | — | — | US | claimed |
| US-20260003210-A1 | DIFFRACTIVE CONTACT LENSES | ALCON INC (CH) | 2026-01-01 | — | — | US | claimed |
| US-12379611-B2 | Diffractive contact lenses | ALCON INC. (CH) | 2025-08-05 | — | — | US | claimed |
| EP-4522406-A1 | METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES | Alcon Inc. (CH) | 2025-03-19 | — | — | EP | claimed |
| EP-4514595-A1 | METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES | Alcon Inc. (CH) | 2025-03-05 | — | — | EP | claimed |
| EP-4121802-B1 | HIGH REFRACTIVE INDEX SILOXANE INSERT MATERIALS FOR EMBEDDED CONTACT LENSES | ALCON INC (CH) | 2024-07-17 | — | — | EP | claimed |
| EP-4356169-A1 | MULTIFOCAL DIFFRACTIVE SILICONE HYDROGEL CONTACT LENSES | Alcon Inc. (CH) | 2024-04-24 | — | — | EP | claimed |
| EP-4121801-B1 | INSERT MATERIALS WITH HIGH OXYGEN PERMEABILITY AND HIGH REFRACTIVE INDEX | ALCON INC (CH) | 2024-04-17 | — | — | EP | claimed |
| CN-117467059-A | Polymer porous microsphere and preparation method and application thereof | 西安蓝晓科技新材料股份有限公司 | 2024-01-30 | — | — | CN | claimed |
| US-20170342185-A1 | PHOSPHORUS-CONTAINING OLEFIN POLYMER, METHOD FOR PREPARING THE SAME, AND COMPOSITION AND ARTICLE COMPRISING THE SAME | Elite Material Co., Ltd. (TW) | 2017-11-30 | — | — | US | claimed |
| US-20130115543-A1 | THERMOSTABLE POLYMER ELECTROLYTE MEMBRANE AND PROCESS FOR PRODUCING THE SAME | JAPAN ATOMIC ENERGY AGENCY (JP) | 2013-05-09 | — | — | US | claimed |
| US-7803846-B2 | Highly durable polymer electrolytic membrane for a fuel cell having a cross-linked structure | JAPAN ATOMIC ENERGY AGENCY (JP) | 2010-09-28 | — | — | US | claimed |
| US-20060134493-A1 | Highly durable polymer electrolytic membrane for a fuel cell having a cross-linked structure | JAPAN ATOMIC ENERGY AGENCY (JP) | 2006-06-22 | — | — | US | claimed |
| US-6627720-B2 | Monoethylenically unsaturated monomers are polymerized with at least one multiethylenically unsaturated monomer at high temperatures by free radical polymerization in a continuous reactor, without formation of highly crosslinked gels | JOHNSON POLYMER, LLC | 2003-09-30 | — | — | US | claimed |
| US-6265511-B1 | BLEND OF DIVINYL MONOMER AND MONOETHYLENICALLY UNSATURATED MONOMER | S. C. JOHNSON COMMERICAL MARKETS, INC. | 2001-07-24 | — | — | US | claimed |
| US-5663260-A | Hyperbranched copolymers from AB monomers and C monomers | CORNELL RESEARCH FOUNDATION, INC. (US) | 1997-09-02 | — | — | US | claimed |
| US-5587441-A | Hyperbranched polymers from AB monomers | CORNELL RESEARCH FOUNDATION, INC. (US) | 1996-12-24 | — | — | US | claimed |
| US-4234674-A | Amino-functional photopolymer compositions and photo-oxidation imaging processes employing same | MONSANTO COMPANY (US) | 1980-11-18 | — | — | US | claimed |
| US-4188223-A | Amino-functional photopolymer compositions and photo-oxidation imaging processes employing same | MONSANTO COMPANY (US) | 1980-02-12 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12539650-B2 | Method for making embedded hydrogel contact lenses | INF2, CRYZ, CRYAA | ALDH1A1 1404/4885TSHR 2876/4885TDP1 4498/4885 |
| US-20260003210-A1 | DIFFRACTIVE CONTACT LENSES | LBR, CRYZ, CRYAA | ALDH1A1 1323/4885TSHR 1437/4885TDP1 2489/4885 |
| US-12570784-B2 | Method for making embedded hydrogel contact lenses | CRYAB, CRYZ, CRYAA | ALDH1A1 2345/4885TSHR 3379/4885TDP1 4551/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.