Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3773036 | 0.89 | MTNR1A (0.41) | MTNR1AMTNR1BKCNH2SIGMAR1SMPD1 | |
| SCHEMBL3772489 | 0.84 | MTNR1A (0.33) | MTNR1AMTNR1B | |
| SCHEMBL3765419 | 0.83 | MTNR1A (0.34) | MTNR1AMTNR1B | |
| SCHEMBL3768193 | 0.80 | MAPT (0.35) | MTNR1AMTNR1BKCNH2KDM4EL3MBTL1 | |
| SCHEMBL3770911 | 0.79 | MTNR1A (0.30) | MTNR1AMTNR1BTAAR1 | |
| SCHEMBL3769710 | 0.79 | MEN1 (0.32) | MTNR1AMTNR1B | |
| SCHEMBL3772474 | 0.78 | MTNR1A (0.32) | MTNR1AMTNR1B | |
| SCHEMBL3769753 | 0.77 | MTNR1A (0.33) | MTNR1AMTNR1B | |
| SCHEMBL18806263 | 0.77 | MEN1 (0.41) | MTNR1AMTNR1BKDM4EL3MBTL1MAPT | |
| SCHEMBL3768242 | 0.77 | GAA (0.41) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8436166-B2 | Amino-containing vinylsilane compounds and making method | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2013-05-07 | — | — | US | disclosed |
| US-20100317852-A1 | AMINO-CONTAINING VINYLSILANE COMPOUNDS AND MAKING METHOD | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2010-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317852-A1 | AMINO-CONTAINING VINYLSILANE COMPOUNDS AND MAKING METHOD | BHMT2, GNMT, VASP | MTNR1A 4342/4885MTNR1B 4325/4885KCNH2 3841/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.