Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | MARK3 | P27448 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | MARK2 | Q7KZI7 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9641861 | 0.84 | PARP1 (0.37) | PARP1PARP10NOTUMAURKACHEK2 | |
| SCHEMBL29756225 | 0.83 | NOX1 (0.38) | PARP1PARP10BLMNOTUMAURKA | |
| SCHEMBL566630 | 0.82 | PARP1 (0.40) | PARP1PARP10NOTUMACHEGPR84 | |
| SCHEMBL5543938 | 0.78 | DRD2 (0.33) | PARP1PARP10NOTUMAURKACHEK2 | |
| SCHEMBL16710755 | 0.76 | METAP1 (0.42) | PARP1PARP10BLMALDH1A1LMNA | |
| SCHEMBL9700006 | 0.76 | HPGD (0.50) | PARP1PARP10BLMCHEK2PIM1 | |
| SCHEMBL20734693 | 0.75 | BLM (0.32) | BLMALDH1A1HPGDKDM4E | |
| SCHEMBL11704020 | 0.74 | BLM (0.68) | BLMGPR84ALDH1A1LMNAMAPT | |
| SCHEMBL11172784 | 0.72 | HTT (0.47) | BLMALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL20123505 | 0.71 | AURKA (0.44) | NOTUMAURKACHEK2CDK1PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7847119-B2 | Drug conjugates | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2010-12-07 | — | — | US | disclosed |
| US-7438993-B2 | Electrolyte for lithium battery and lithium battery comprising same | SAMSUNG SDI CO., LTD. (KR) | 2008-10-21 | — | — | US | disclosed |
| US-7438993-B2 | Electrolyte for lithium battery and lithium battery comprising same | SAMSUNG SDI CO., LTD. (KR) | 2008-10-21 | — | — | US | disclosed |
| US-20080139815-A1 | DRUG CONJUGATES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-06-12 | — | — | US | disclosed |
| US-7282590-B2 | Selectively target tumor cells with highly potent cytotoxic drugs at a drug release rate that is effective for the destruction and/or inhibition of tumor cells | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2007-10-16 | — | — | US | disclosed |
| US-20050232928-A1 | Drug conjugates | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-10-20 | — | — | US | disclosed |
| US-5147889-A | Antiinflammatory, analgesic | CIBA-GEIGY CORPORATION (US) | 1992-09-15 | — | — | US | disclosed |
| EP-0336886-B1 | THIO COMPOUNDS | CIBA-GEIGY AG (CH) | 1992-08-26 | — | — | EP | disclosed |
| US-5051421-A | Analgesics and antiinflammatory agents | CIBA-GEIGY CORPORATION (US) | 1991-09-24 | — | — | US | disclosed |
| EP-0336886-A1 | Thio compounds | CIBA-GEIGY AG (CH) | 1989-10-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050232928-A1 | Drug conjugates | RXRB, NR0B1, RXRA | PARP1 1511/4885PARP10 1509/4885BLM 1831/4885 |
| US-20080139815-A1 | DRUG CONJUGATES | RXRB, NR0B1, RXRA | PARP1 1574/4885PARP10 1568/4885BLM 1813/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.