SCHEMBL3765755

SCHEMBL3765755

CCCO[Si](CCCO)(OCCC)OCCC

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.38
LMNA P02545 2/20 0.36
TSHR P16473 2/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
HSD17B10 Q99714 1/20 0.36
ACHE P22303 7/20 0.32
THRB P10828 1/20 0.32
HTT P42858 1/20 0.32
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8159668 0.93 SMN1; SMN2 (0.42) ALDH1A1SMN1; SMN2LMNATSHRMEN1
SCHEMBL702188 0.85 LMNA (0.31) LMNA
SCHEMBL431790 0.85 LMNA (0.31) LMNA
SCHEMBL29512548 0.82 LMNA (0.34) LMNATSHRTHRB
SCHEMBL13268839 0.82 LMNA (0.34) LMNATSHRTHRB
SCHEMBL109400 0.82 LMNA (0.34) LMNATSHRTHRB
SCHEMBL8512727 0.82 LMNA (0.34) LMNATSHRTHRB
SCHEMBL190937 0.80 ALDH1A1 (0.36) ALDH1A1SMN1; SMN2LMNATSHRMEN1
SCHEMBL2396676 0.80 LMNA (0.38) LMNATSHRMEN1KMT2ATHRB
Water SCHEMBL27827345 0.80 LMNA (0.33) LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9637601-B2 Method for preparing a masterbatch of an elastomer and an inorganic reinforcing filler COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2017-05-02 US claimed
CN-104053676-B Process for preparing a masterbatch of elastomer and inorganic reinforcing filler 米其林集团总公司 2017-03-15 CN claimed
EP-2697266-B1 METHOD FOR PREPARING A MASTERBATCH OF AN ELASTOMER AND AN INORGANIC REINFORCING FILLER MICHELIN & CIE (FR) 2017-02-22 EP claimed
CN-103384683-B Method for preparing a masterbatch in the liquid phase COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2015-11-25 CN claimed
US-9145489-B2 Process for preparing a masterbatch in the liquid phase COMPAGNIE GENERAL DES ETABLISSEMENTS MICHELIN (FR) 2015-09-29 US claimed
US-20150267008-A1 METHOD FOR PREPARING A MASTERBATCH OF AN ELASTOMER AND AN INORGANIC REINFORCING FILLER MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2015-09-24 US claimed
EP-2655422-B1 PROCESS FOR PREPARING A MASTERBATCH IN THE LIQUID PHASE MICHELIN & CIE (FR) 2015-02-25 EP claimed
CN-104053676-A Process for preparing a masterbatch of elastomer and inorganic reinforcing filler MICHELIN & CIE 2014-09-17 CN claimed
EP-2697266-A1 METHOD FOR PREPARING A MASTERBATCH OF AN ELASTOMER AND AN INORGANIC REINFORCING FILLER Compagnie Générale des Etablissements Michelin (FR) 2014-02-19 EP claimed
CN-103384683-A Method for preparing a masterbatch in the liquid phase MICHELIN RECH TECH 2013-11-06 CN claimed
EP-2655422-A1 PROCESS FOR PREPARING A MASTERBATCH IN THE LIQUID PHASE Compagnie Générale des Etablissements Michelin (FR) 2013-10-30 EP claimed
WO-2012139669-A1 METHOD FOR PREPARING A MASTERBATCH OF AN ELASTOMER AND AN INORGANIC REINFORCING FILLER COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2012-10-18 WO claimed
WO-2012085137-A1 PROCESS FOR PREPARING A MASTERBATCH IN THE LIQUID PHASE COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2012-06-28 WO claimed
US-11421097-B2 Container sealant composition HENKEL AG & CO. KGAA (DE) 2022-08-23 US disclosed
CN-111902447-A Process for preparing polyurethane flexible foam 科思创知识产权两合公司 2020-11-06 CN disclosed
US-9637601-B2 Method for preparing a masterbatch of an elastomer and an inorganic reinforcing filler COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2017-05-02 US disclosed
EP-0849320-B1 Process for mixing silica in a polymer latex DSM COPOLYMER INC (US) 2002-04-03 EP disclosed
US-5985953-A Compatibilized silica and polymer silica-reinforced masterbatch containing same DSM COPOLYMER, INC. (US) 1999-11-16 US disclosed
EP-0849320-A1 Compatibilized silica and polymer silica-reinforced masterbatch containing same DSM Copolymer, Inc. (US) 1998-06-24 EP disclosed
US-5763388-A Process for producing improved silica-reinforced masterbatch of polymers prepared in latex form DSM COPOLYMER, INC. (US) 1998-06-09 US disclosed