SCHEMBL3765775

SCHEMBL3765775

Cc1noc(NC(=O)N2CCN(c3nc(-c4cccs4)ns3)CC2)c1C

nearest known ligand 0.54

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
FAAH O00519 17/20 0.54
GALR3 O60755 1/20 0.45
NR2F2 P24468 1/20 0.45
RAB9A P51151 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3765680 0.86 FAAH (0.73) FAAHRAB9A
SCHEMBL3777232 0.83 FAAH (0.76) FAAH
SCHEMBL3766291 0.82 FAAH (0.74) FAAH
SCHEMBL3767632 0.81 FAAH (0.75) FAAHGALR3NR2F2RAB9A
SCHEMBL4481269 0.80 FAAH (0.74) FAAH
SCHEMBL3772014 0.79 FAAH (0.74) FAAH
SCHEMBL3772092 0.79 FAAH (0.77) FAAH
SCHEMBL3765815 0.77 FAAH (0.68) FAAHGALR3NR2F2RAB9A
SCHEMBL3763289 0.76 FAAH (0.51) FAAHRAB9A
SCHEMBL3763267 0.76 FAAH (0.74) FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150291578-A1 FUNGICIDAL AZOCYCLIC AMIDES CORTEVA AGRISCIENCE LLC 2015-10-15 US claimed
US-8642634-B2 Fungicidal azocyclic amides E I DU PONT DE NEMOURS AND COMPANY (US) 2014-02-04 US claimed
US-7851473-B2 Amide compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2010-12-14 US disclosed
US-20080312226-A1 Amide Compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2008-12-18 US disclosed
EP-1813606-A1 AMIDE COMPOUND Takeda Pharmaceutical Company Limited (JP) 2007-08-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080312226-A1 Amide Compound FAAH, FAAH2, CNR2 FAAH 1/4885GALR3 1024/4885NR2F2 2521/4885
US-20150291578-A1 FUNGICIDAL AZOCYCLIC AMIDES ARG1, NAT1, CHRM1 FAAH 3561/4885GALR3 2245/4885NR2F2 3287/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.